TRIMETHOPRIM-RESISTANT ESCHERICHIA-COLI IN HOUSEHOLDS OF CHILDREN ATTENDING DAY-CARE-CENTERS
TRIMETHOPRIM-RESISTANT ESCHERICHIA-COLI IN HOUSEHOLDS OF CHILDREN ATTENDING DAY-CARE-CENTERS
复制标题
DOI：
10.1093/infdis/166.2.326
复制
发表时间：
1992-08-01
影响因子：
6.4
通讯作者：
PICKERING, LK
中科院分区：
文献类型：
--
作者：
FORNASINI, M;REVES, RR;PICKERING, LK
日托中心的儿童经常感染耐甲氧苄啶的大肠杆菌。研究了向家庭成员传播的频率。23名日托中心儿童中有13名（57%）检出耐甲氧苄啶大肠杆菌定植。在接受测试的51个家庭成员中的50个（98%）中，有13个（26%）检测到定植，即在接受测试的23个家庭中有12个（52%）。移民中心儿童家庭的移民成员明显多于非移民儿童家庭（优势比为13.3；95%可信区间为1.3-172.6;P = 0.01）。母亲（35%）和兄弟姐妹（30%）的殖民化发生率高于父亲（12%）。在12个定殖家庭中，8个（67%）中心儿童中发现了相同的耐甲氧苄啶大肠杆菌质粒谱。抗生素使用与耐甲氧苄啶大肠杆菌的粪便定植之间没有关联。因此，耐甲氧苄啶的大肠杆菌在日托中心的儿童之间以及从中心儿童到家庭成员之间的传播是常见的。
Children in day care centers are frequently colonized with trimethoprim-resistant Escherichia coli. The frequency of transmission to family members was studied. Colonization with trimethoprim-resistant E. coli was detected in 13 (57%) of 23 day care center children. Among the 50 (98%) of 51 household members tested, colonization was detected in 13 (26%), representing 12 (52%) of 23 households tested. Households of colonized center children had significantly more colonized members than did households of noncolonized children (odds ratio, 13.3; 95% confidence interval, 1.3-172.6; P = .01). There was a trend toward higher prevalence of colonization in mothers (35%) and siblings (30%) than in fathers (12%). The same plasmid profiles of trimethoprim-resistant E. coli from center children were found among 8 (67%) of 12 colonized households. There was no association between antibiotic use and fecal colonization with trimethoprim-resistant E. coli. Thus, transmission of trimethoprim-resistant E. coli among children within day care centers and from center children to household members is common.