Prevalence of dry eye syndrome among US women
Prevalence of dry eye syndrome among US women
复制标题
DOI：
10.1016/s0002-9394(03)00218-6
复制
发表时间：
2003-08-01
影响因子：
4.2
通讯作者：
Dana, MR
中科院分区：
文献类型：
--
作者：
Schaumberg, DA;Sullivan, DA;Dana, MR
干眼综合征（DES）被认为是美国最常见的眼部问题之一，尤其是在老年妇女中。然而，很少有研究描述的问题，在妇女的规模，这可能会随着人口统计学特征。设计：横断面患病率survey.METHODS：研究人群：我们调查了39,876名美国妇女参加妇女健康研究的历史诊断DES和干眼症状。主要结果测量：我们将DES定义为临床诊断的DES或严重症状（持续或经常干燥和刺激）的存在。我们计算了DES的年龄特异性患病率，并根据美国人群中女性的年龄分布调整了总体患病率。我们使用逻辑回归来检验DES和其他人口统计学因素之间的关联。结果：DES的患病率随着年龄的增长而增加，从50岁以下女性的5.7%增加到75岁以下女性的9.8%。DES的年龄调整患病率为7.8%，或323万美国50岁以下女性。与白人相比，西班牙裔（比值比[OR] = 1.81，置信区间[CI] = 1.18-2.80）和亚裔（OR = 1.77，CI = 1.17-2.69）女性更有可能报告严重症状，但未临床诊断为DES。收入差异无显著性（P-[趋势] = 0.78），但受教育程度较高的女性患DES的可能性较低（P-[趋势] = 0.03）。来自南方的妇女DES的患病率最高，虽然地理差异的幅度是moderate.CONCLUSIONS：干眼症导致临床诊断或严重症状是普遍的，影响超过320万美国妇女中，老年人和老年人。虽然这种情况在老年妇女中更为普遍，但它也影响到许多40多岁和50多岁的妇女。需要进一步的研究来更好地了解DES及其对公众健康和生活质量的影响。
PURPOSE: Dry eye syndrome (DES) is believed to be one of the most common ocular problems in the United States (US), particularly among older women. However, there are few studies describing the magnitude of the problem in women and how this may vary with demographic characteristics.DESIGN: Cross-sectional prevalence survey.METHODS: Study population: we surveyed 39,876 US women participating in the Women's Health Study about a history of diagnosed DES and dry eye symptoms. Main outcome measure: we defined DES as the presence of clinically diagnosed DES or severe symptoms (both dryness and irritation constantly or often). We calculated the age-specific prevalence of DES and adjusted the overall prevalence to the age distribution of women in the US population. We used logistic regression to examine associations between DES and other demographic factors.RESULTS: The prevalence of DES increased with age, from 5.7% among women < 50 years old to 9.8% among women aged : 75 years old. The age-adjusted prevalence of DES was 7.8%, or 3.23 million women aged : 50 in the US. Compared with Whites, Hispanic (odds ratio [OR] = 1.81, confidence interval [CI] = 1.18-2.80) and Asian (OR = 1.7 7, CI = 1.17-2.69) women were more likely to report severe symptoms, but not clinically diagnosed DES. There were no significant differences by income (P-[trend] =.78), but more educated women were less likely to have DES (P-[trend] =.03). Women from the South had the highest prevalence of DES, though the magnitude of geographic differences was modest.CONCLUSIONS: Dry eye syndrome leading to a clinical diagnosis or severe symptoms is prevalent, affecting over 3.2 million American women middle,aged and older. Although the condition is more prevalent among older women, it also affects many women in their 40s and 50s. Further research is needed to better understand DES and its impact on public health and quality of life.