Apoyo con Carino: Strategies to Promote Recruiting, Enrolling, and Retaining Latinos in a Cancer Clinical Trial
Apoyo con Carino: Strategies to Promote Recruiting, Enrolling, and Retaining Latinos in a Cancer Clinical Trial
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DOI：
10.6004/jnccn.2017.7005
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发表时间：
2017-11-01
影响因子：
13.4
通讯作者：
Fink, Regina M.
中科院分区：
文献类型：
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作者：
Fischer, Stacy M.;Kline, Danielle M.;Fink, Regina M.
背景：我们提出并描述了量身定制的策略，以解决少数人参与临床试验研究的已知障碍。所使用的策略使我们的团队能够参与社区，并成功地招募，招募和保留了患有晚期癌症的拉丁美洲人的多样化服务不足人群。方法：参与者从3个城市和7个农村站点招募。我们确定了这一服务不足人群招募的4个关键障碍：（1）不信任;（2）语言和沟通障碍;（3）缺乏进入学术癌症中心的机会;（4）由于交通，儿童保育或工作责任而无法参与。我们制定了量身定制的策略，以吸引转介研究中心和患者参与临床试验。结果如下：我们确定了318名潜在合格的参与者; 34名被发现不合格，223名同意参加研究，代表79.0%的入组率。所有患者（100%）自我认定为拉丁美洲人，47.5%的人说西班牙语作为他们的主要语言。患者在社会经济上处于不利地位：53.6%的患者有年收入
Background: We present and describe tailored strategies to address known barriers to minority participation in clinical trial research. The strategies used allowed our team to engage communities and successfully recruit, enroll, and retain a diverse underserved population of Latinos with advanced cancer for this clinical trial. Methods: Participants were recruited from 3 urban and 7 rural sites. We identified 4 critical barriers to recruitment for this underserved population: (1) mistrust; (2) language and communication barriers; (3) lack of access to academic cancer center; and (4) inability to participate due to transportation, childcare, or work responsibilities. We developed tailored strategies to engage referring sites and patients to participate in the clinical trial. Results: We identified 318 potentially eligible participants; 34 were found to be ineligible, and 223 consented to participate in the study, representing a 79.0% enrollment rate. All patients (100%) self-identified as Latino, and 47.5% spoke Spanish as their primary language. Patients were socioeconomically disadvantaged: 53.6% had an annual income