Management of the neck in patients with T1 and T2 cancer in the mouth
Management of the neck in patients with T1 and T2 cancer in the mouth
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DOI：
10.1016/j.bjoms.2004.06.013
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发表时间：
2004-12-01
影响因子：
1.8
通讯作者：
Gao, K
中科院分区：
文献类型：
--
作者：
Smith, GI;O'Brien, CJ;Gao, K
我们的目的是在这一回顾性研究是评估转移性疾病的控制程度在颈部和T1和T2口腔cancer.Methods患者的生存：所有171例T1和T2口腔鳞状细胞癌（SCC）从我们的计算机化数据库中确定。所有患者均行原发肿瘤切除术，21例可触及颈部淋巴结的患者行治疗性颈部淋巴结清扫术。在150例未触及淋巴结的患者中，75例进行了选择性颈淋巴结清扫术，75例进行了观察。决定做一个选择性颈淋巴结清扫术是基于临床标准，并没有randomized.Results：颈淋巴结转移包含在17的21例患者谁有治疗，和27的75谁有选择性，颈淋巴结清扫术。观察组75例患者中有15例随后发生颈部转移，其中9例通过治疗性颈淋巴结清扫术得以挽救。治疗性切除后5年无瘤生存率为19/21，选择性切除后为72/75，观察组为69/75。有颈淋巴结转移的患者5年生存率显著低于无颈淋巴结转移的患者（63%和91%，P = 0.003）。(C)2004年英国口腔颌面外科医师协会。由爱思唯尔有限公司出版。保留所有权利。
Our aim in this restrospective study was to evaluate the extent of control of metastatic disease in the neck and the survival of patients with T1 and T2 oral cancer.Methods: All 171 patients with T1 and T2 squamous cell carcinoma (SCC) in the mouth were identified from our computerised database. All had had primary tumours resected and 21 patients with palpable neck nodes had therapeutic neck dissections. Among 150 patients with no palpable nodes, 75 had elective neck dissections, and 75 were observed. The decision to do an elective neck dissection was based on clinical criteria and was not randomised.Results: Cervical nodes contained metastases in 17 of 21 patients who had therapeutic, and 27 of 75 who had elective, neck dissections. Neck metastases developed subsequently in 15 of 75 patients in the observed group, and 9 of these were salvaged by therapeutic neck dissection. The 5-year disease free survival was 19/21 after therapeutic dissection, 72/75 after elective dissection, and 69/75 in the observed group. Patients with cervical nodal metastases had significantly reduced 5-year survival compared with those without (63% and 91%, P = 0.003). (C) 2004 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.