Serum biochemistry panels in African buffalo: Defining reference intervals and assessing variability across season, age and sex.
Serum biochemistry panels in African buffalo: Defining reference intervals and assessing variability across season, age and sex.
复制标题
DOI：
10.1371/journal.pone.0176830
复制
发表时间：
2017
期刊：
影响因子：
3.7
通讯作者：
Beechler BR
中科院分区：
文献类型：
--
作者：
Couch CE;Movius MA;Jolles AE;Gorman ME;Rigas JD;Beechler BR
血清生化指标可以用来评价动物的生理状态，并将其与动物的健康状况联系起来。为了准确解释个体动物的生化结果，必须建立种属特异性参考区间（RI）。生化参数的参考区间在物种之间不同，并且生理差异包括生殖状态、营养资源可用性、疾病状态和年龄影响同一物种内的参数。本研究的目的是（1）建立管理的非洲布法罗（Syncerus caffer）生化参数的RI，（2）评估年龄、性别、妊娠和季节对血清生化值的影响，（3）比较管理牛群与自由放养的布法罗牛群的血清生化值以及先前发表的圈养（动物园）布法罗的值。季节深刻地影响了所有的生化参数，可能是由于营养和疾病暴露的变化。年龄还影响了除γ-谷氨酰转移酶和镁以外的所有生化参数，与牛中观察到的模式一致。性别和生殖状态对测量的参数没有可检测的影响。管理的布法罗的生化特征与自由放养的牛群和圈养的布法罗不同。布法罗从圈养，管理和自由放养的人口之间的生化差异可能与营养限制或缺乏捕食的背景下，管理或圈养。除了观察到的季节性和年龄相关模式外，本研究中提供的参考区间还为健康调查提供了基础，这些调查可能会为这一具有生态和经济重要性的物种的管理策略提供信息。
Serum biochemical parameters can be utilized to evaluate the physiological status of an animal, and relate it to the animal’s health. In order to accurately interpret individual animal biochemical results, species-specific reference intervals (RI) must be established. Reference intervals for biochemical parameters differ between species, and physiological differences including reproductive status, nutritional resource availability, disease status, and age affect parameters within the same species. The objectives of this study were to (1) establish RI for biochemical parameters in managed African buffalo (Syncerus caffer), (2) assess the effects of age, sex, pregnancy, and season on serum biochemistry values, and (3) compare serum biochemistry values from a managed herd to a free-ranging buffalo herd and to values previously published for captive (zoo) buffalo. Season profoundly affected all biochemistry parameters, possibly due to changes in nutrition and disease exposure. Age also affected all biochemical parameters except gamma glutamyl transferase and magnesium, consistent with patterns seen in cattle. Sex and reproductive status had no detectable effects on the parameters that were measured. The biochemical profiles of managed buffalo were distinct from those observed in the free-ranging herd and captive buffalo. Biochemical differences between buffalo from captive, managed, and free-ranging populations may be related to nutritional restriction or lack of predation in the context of management or captivity. The reference intervals provided in this study, in addition to the seasonal and age-related patterns observed, provide a foundation for health investigations that may inform management strategies in this ecologically and economically important species.