Ecologic analysis of antimicrobial use in South Carolina hospitals during 2020-2022.
Ecologic analysis of antimicrobial use in South Carolina hospitals during 2020-2022.
复制标题
DOI：
10.1017/ash.2023.496
复制
发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Zhang, Jiajia
中科院分区：
文献类型：
--
作者：
Bailey, Pamela;Chen, Shujie;Al-Hasan, Majdi N;Olatosi, Bankole;Li, Xiaoming;Zhang, Jiajia
影响住院患者过度使用抗菌药物的因素仍然知之甚少，特别是在COVID-19大流行的情况下。在该回顾性队列中，我们比较了2020年3月至2022年9月南卡罗来纳州住院患者抗菌药物处方的管理数据。该研究检查了与人口统计学，COVID状态和住院时间等变量中的抗菌药物使用相关的变量。在COVID-19阳性患者中观察到与抗菌药物使用的显著关系（OR 2.00，95%置信区间（CI）：1.9-2.1），年轻成人（OR 1.08，95% CI：0.99-1.12，COVID-19阳性黑人和西班牙裔（OR 1.06，95% CI：1.01-1.11，OR 1.05，95% CI：0.89-1.23），以及COVID-19阳性患者伴≥2种共病（OR 1.55，95%CI：1.43-1.68）。在一个以上的医疗保健系统的进一步分析应该进一步探索这些生态关系，以了解这些是否是共同的趋势，以告知正在进行的管理干预。
Factors influencing excessive antimicrobial utilization in hospitalized patients remain poorly understood, particularly with the COVID-19 pandemic. In this retrospective cohort, we compared administrative data regarding antimicrobial prescriptions in hospitalized patients in South Carolina from March 2020 through September 2022. The study examined variables associated with antimicrobial use across demographics, COVID status, and length of stay, among other variables. Significant relationships were seen with antimicrobial use in COVID-19 positive patients (OR 2.00, 95% Confidence Interval (CI): 1.9–2.1), young adults (OR 1.08, 95% CI: 0.99–1.12, COVID-19 positive Blacks and Hispanics (OR 1.06, 95% CI: 1.01–1.11, OR 1.05, 95% CI: 0.89–1.23), and COVID-19 positive patients with ≥2 comorbid conditions (OR 1.55, 95% CI: 1.43–1.68). Further analysis in more than one healthcare system should explore these ecologic relationships further to understand if these are common trends to inform ongoing stewardship interventions.
影响因子：
3.4
作者：
通讯作者：
--