Gold-Catalyzed Nucleophilic Ring-Opening Reaction of 2-Alkynylazetidines with Alcohols
Gold-Catalyzed Nucleophilic Ring-Opening Reaction of 2-Alkynylazetidines with Alcohols
复制标题
金催化 2-炔基氮杂环丁烷与醇的亲核开环反应
DOI：
10.1021/acs.joc.2c01325
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
M.
中科院分区：
文献类型：
--
作者：
Hirokane;T.; Kariya;T.; Takata;M.; Matsumoto;K.; Yoshida;M.
本文报道了2-烷基氮杂环丁烷与醇在金催化剂上的反应。通过醇的金促进的亲核攻击和氮杂环的开环反应，合成了一系列取代的δ-氨基-α，β-不饱和酮。
The reaction of 2-alkynylazetidines and alcohols with a gold catalyst is described. A variety of substituted δ-amino-α,β-unsaturated ketones were synthesized via gold-promoted nucleophilic attack of alcohols followed by ring-opening of azetidine ring.