Ouija board: A transcription factor evolved for only one target in steroid hormone biosynthesis in the fruit fly Drosophila melanogaster.
Ouija board: A transcription factor evolved for only one target in steroid hormone biosynthesis in the fruit fly Drosophila melanogaster.
复制标题
DOI：
10.1080/21541264.2016.1210370
复制
发表时间：
2016-10-19
期刊：
影响因子：
--
通讯作者：
Niwa R
中科院分区：
文献类型：
--
作者：
Niwa YS;Niwa R
转录因子通常调控多个靶点的基因表达。相比之下，我们最近的发现表明锌指蛋白Ouija板通过对果蝇中一个更怪异的基因的特定调节来控制类固醇激素的生物合成。它揭示了为一个目标而进化的一个专门但重要的因素。
Transcription factors generally regulate gene expression of multiple targets. In contrast, our recent finding suggests that the zinc finger protein Ouija board controls steroid hormone biosynthesis through specific regulation of only one gene spookier in Drosophila. It sheds light on a specialized but essential factor that evolved for one target.