Tobacco industry sponsorship of a book and conflict of interest

Tobacco industry sponsorship of a book and conflict of interest
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DOI:
10.1111/j.1360-0443.2007.01382.x
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发表时间:
2006-08-01
期刊:
影响因子:
6
通讯作者:
Bero, Lisa A.
Bero, Lisa A.
中科院分区:
医学1区
文献类型:
--
作者:
Hong, Mi-Kyung;Bero, Lisa A.

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目的 烟草业隐藏其对科学研究文章的设计、实施和出版的参与,并利用这些文章来反对烟草监管。本研究的目的是调查烟草业参与科学书籍开发的情况。设计 对从传统烟草文档库 (http://legacy.library.ucsf.edu) 检索到的以前秘密的烟草行业内部文件进行定性分析。这些文件中的信息还通过互联网搜索、国家生物技术信息中心 Pubmed 数据库以及对参与书籍出版的个人的采访来补充。研究结果 1997 年至 1999 年间,烟草业赞助了一本题为“尼古丁和相关化合物及其代谢物的分析测定”的专着,该专着研究了尼古丁的测量和代谢。烟草业聘请爱思唯尔科学出版该专着。烟草行业高管、律师和科学家审阅了这些章节。该专着的用途之一是促进学术界和烟草业科学家之间的合作。另一个目标是向政府监管机构提供这本书,审查尼古丁的致畸作用。结论 我们的研究结果显示了烟草业参与科学知识生产和传播的广度及其赞助科学文献的动机。该行业通过与学术科学家合作来获得信誉的努力引发了有关接受烟草行业出版资助的道德问题。与烟草业赞助的出版物合作的科学家必须考虑这些共同努力的全面影响。
Aim The tobacco industry has hidden its involvement in the design, conduct and publication of scientific research articles and has used the articles to argue against tobacco regulation. The objective of this study is to examine tobacco industry involvement in the development of scientific books. Design Qualitative analysis of previously secret internal tobacco industry documents retrieved from the Legacy Tobacco Documents Library (http://legacy.library.ucsf.edu). Information from the documents was supplemented with material from Internet searches, the National Center for Biotechnology Information Pubmed database and interviews with individuals involved in book publication. Findings Between 1997 and 1999 the tobacco industry sponsored a monograph, entitled 'Analytical Determination of Nicotine and Related Compounds and their Metabolites', that examined the measurement and metabolism of nicotine. The tobacco industry recruited Elsevier Science to publish the monograph. Tobacco industry executives, lawyers and scientists reviewed the chapters. One use of the monograph was to stimulate collaborative efforts between academic and tobacco industry scientists. Another was to provide the book to a government regulatory agency reviewing the teratogenic effects of nicotine. Conclusion Our findings show the breadth of tobacco industry engagement in scientific knowledge production and dissemination, and its motives for sponsoring scientific literature. The industry's effort to gain credibility through collaboration with academic scientists raises questions regarding the ethics of accepting tobacco industry funding for publication. Scientists who collaborate on publications sponsored by the tobacco industry must consider the full implications of these joint efforts.