EEG spectral analysis in migraine without aura attacks
EEG spectral analysis in migraine without aura attacks
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DOI：
10.1046/j.1468-2982.1998.1806324.x
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发表时间：
1998-07-01
期刊：
影响因子：
4.9
通讯作者：
Puca, FM
中科院分区：
文献类型：
--
作者：
de Tommaso, M;Sciruicchio, V;Puca, FM
在 16 名无先兆偏头痛患者中，我们检查了偏头痛关键期和无发作期 27 Hz 刺激下的定量脑电图和稳态视觉诱发电位 (SSVEP)。在关键阶段发现的主要自发脑电图异常是α范围内主频率的减慢和不对称。与临界间期相比，攻击期SSVEP Fl分量的幅度显着减小；在后一种情况下，与正常受试者相比，几乎整个头皮对 27 Hz 刺激的视觉反应有所增加。脑电图异常证实了偏头痛发作期间α活性的波动性改变，可能与功能障碍有关。偏头痛发作期间视觉反应性的抑制可能与神经元去极化现象有关，例如在中枢神经元兴奋性增加的情况下发生的扩散性抑郁，易诱发偏头痛发作。
In 16 patients suffering from migraine without aura, we examined quantitative EEG and steady-state visual evoked potentials (SSVEPs) at 27 Hz stimulation during the critical phase of migraine and in attack-free periods. The main spontaneous EEG abnormalities found during the critical phase were the slowing and asymmetry of the dominant frequency in the alpha range. The amplitude of the SSVEP Fl component was significantly reduced during the attack phase compared with the intercritical phase; in the latter condition the visual reactivity to 27 Hz stimulus was increased over almost the entire scalp compared with normal subjects. The EEG abnormalities confirm a fluctuating modification of alpha activity during the migraine attack, probably related to a functional disorder. The suppression of visual reactivity during the migraine attack could be related to a phenomenon of neuronal depolarization such as spreading depression, occurring in a situation of central neuronal increased excitability predisposing to migraine attacks.