Fermentative production of gluconic acid: A membrane-integrated Green process
Fermentative production of gluconic acid: A membrane-integrated Green process
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DOI：
10.1016/j.jtice.2018.01.030
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发表时间：
2018-03-01
影响因子：
5.7
通讯作者：
Pal, Parimal
中科院分区：
文献类型：
--
作者：
Banerjee, Subhamay;Kumar, Ramesh;Pal, Parimal
将下游基于膜的分离模块与传统发酵装置集成，葡萄糖酸是一类重要的工业有机酸，可以通过甘蔗汁发酵生产，这是一种可再生的廉价碳源，对环境无害。以氧化葡萄杆菌为微生物剂进行生物转化，膜集成杂交发酵体系可生产纯度为98%的葡萄糖酸93 g/L，产率为0.94 g/g，产率为6.7 g/L/h。系统性能参数证明了该新技术相对于现有技术的优越性。与涉及多个能源密集型单元操作的绝大多数批次或半批次工艺相比，这种连续生产方案确保了在高度工艺强化的相当简化的工厂中有效的生物转化，而没有底物-产物抑制。（三）2018年台湾省化学工程师学会。Elsevier B.V.版权所有。
On integrating downstream membrane based separation modules with conventional fermentation unit, gluconic acid representing a class of industrially important organic acids could be produced from fermentation of sugar cane juice a renewable cheap carbon source in an environmentally benign process. Using Gluconobacter oxydans as microbial agents in the bioconversion, the membrane-integrated hybrid fermentation system succeeded in producing 93 g/L gluconic acid of 98% purity with yield of 0.94 g/g and productivity of 6.7 g/L/h. The system performance parameters establish superiority of this novel technology over the existing ones. Against the overwhelmingly practiced batch or semi-batch processes involving multiple energy-intensive unit operations, this continuous production scheme ensures efficient bioconversion without substrate-product inhibitions in a quite simplified plant characterized by high degree of process intensification. (C) 2018 Taiwan Institute of Chemical Engineers. Published by Elsevier B.V. All rights reserved.