Childhood Abuse, Intimate Partner Violence and Risk of Migraine Among Pregnant Women: An Epidemiologic Study.
Childhood Abuse, Intimate Partner Violence and Risk of Migraine Among Pregnant Women: An Epidemiologic Study.
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DOI：
10.1111/head.12855
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发表时间：
2016-06
期刊：
影响因子：
5
通讯作者：
Williams MA
中科院分区：
文献类型：
--
作者：
Gelaye B;Do N;Avila S;Carlos Velez J;Zhong QY;Sanchez SE;Peterlin BL;Williams MA
在以前的研究中，儿童虐待和亲密伴侣暴力都与偏头痛有关，但这些关联尚未在孕妇中探索。研究儿童期虐待和亲密伴侣暴力与孕妇偏头痛的独立和联合关联。在秘鲁利马的产前诊所对2 970名孕妇进行了一项横断面研究。童年虐待史（即，身体或性虐待）使用儿童身体和性虐待问卷进行评估。使用世界卫生组织问卷对亲密伴侣暴力（IPV）进行评估。偏头痛分类（包括偏头痛和可能偏头痛）基于国际头痛疾病分类（ICHD）-III β标准。进行多变量logistic回归分析，以估计比值比（OR）和95%置信区间（95%CI）。任何偏头痛的患病率为33.5%，而大约70%的参与者报告了儿童虐待史和36.7%的IPV史。与没有儿童期虐待史的女性相比，有任何儿童期虐待史的女性发生偏头痛的几率增加38%（OR=1.38; 95%CI 1.15-1.64）。偏头痛的几率随着儿童期虐待事件的增加而增加（P趋势<0.001）。此外，在调整混杂因素后，与没有亲密伴侣暴力的女性相比，有IPV病史的女性患偏头痛的几率增加了43%（OR=1.43; 95%CI 1.02-2.02）。与对照组相比，有儿童期虐待和IPV联合阳性史的妇女偏头痛的几率增加88%（aOR=1.88，95%CI：1.51-2.35）。儿童期虐待和IPV与孕妇偏头痛的几率增加有关。我们的研究结果强调了在怀孕的偏头痛患者中进行滥用筛查的重要性，以帮助指导治疗策略。
Childhood abuse and intimate partner violence have each been associated with migraine headaches in previous studies, but these associations have not been explored among pregnant women. To examine the independent and joint associations of childhood abuse and intimate partner violence with migraine among pregnant women. A cross-sectional study was conducted among a cohort of 2,970 pregnant women attending prenatal clinics in Lima, Peru. History of childhood abuse (i.e., physical or sexual abuse) was assessed using the Childhood Physical and Sexual Abuse Questionnaire. Intimate partner violence (IPV) was assessed using the World Health Organization questionnaire. Migraine classification (including migraine and probable migraine) was based on International Classification of Headache Disorders (ICHD)-III beta criteria. Multivariable logistic regression analyses were performed to estimate odd ratios (OR) and 95% confidence intervals (95% CI). The prevalence of any migraine was 33.5% while approximately 70% of participants reported a history of childhood abuse and 36.7% a history of IPV. Women with a history of any childhood abuse had a 38% increased odds of any migraine compared to women with no history of childhood abuse (OR=1.38; 95% CI 1.15-1.64). The odds of migraine increased with increasing numbers of experienced childhood abuse events (Ptrend <0.001). Additionally, after adjusting for confounders women with a history of IPV had a 43% increased odds of any migraine as compared to women without intimate partner violence (OR=1.43; 95%CI 1.02-2.02). Women with a joint positive history of childhood abuse and IPV as compared with the reference group, had a 88% increased odds of migraine (aOR=1.88, 95%CI: 1.51-2.35). Childhood abuse and IPV are associated with increased odds of migraine in pregnant women. Our findings highlight the importance of screening for abuse among pregnant migraineurs to help guide treatment strategies.