10KP: A phylodiverse genome sequencing plan.

10KP: A phylodiverse genome sequencing plan.
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10KP:系统多样性基因组测序计划。

DOI:
10.1093/gigascience/giy013
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发表时间:
2018-03-01
期刊:
影响因子:
9.2
通讯作者:
Wong GK
Wong GK
中科院分区:
生物学2区
文献类型:
--
作者:
Cheng S;Melkonian M;Smith SA;Brockington S;Archibald JM;Delaux PM;Li FW;Melkonian B;Mavrodiev EV;Sun W;Fu Y;Yang H;Soltis DE;Graham SW;Soltis PS;Liu X;Xu X;Wong GK

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在系统基因组学的背景下了解植物的进化和多样性是一个巨大的挑战,部分原因是在系统多样性物种中基因组规模的数据有限。10kp(10,000株植物)基因组测序计划将在未来5年内对胚芽植物、绿藻和原生生物(不包括真菌)的每一个主要分支的代表性基因组进行排序和表征。通过实施和不断改进尖端测序技术和生物信息学工具,10kp将对植物和原生生物多样性的基因组内容进行编目,并使这些数据免费提供,作为未来科学发现和应用的持久基础。10kp是一个国际联合体,向全球社会开放,包括植物园、植物研究所、大学和私营企业。我们的当前目标是为这一努力建立一个政策框架,其原则概述如下。
Understanding plant evolution and diversity in a phylogenomic context is an enormous challenge due, in part, to limited availability of genome-scale data across phylodiverse species. The 10KP (10,000 Plants) Genome Sequencing Project will sequence and characterize representative genomes from every major clade of embryophytes, green algae, and protists (excluding fungi) within the next 5 years. By implementing and continuously improving leading-edge sequencing technologies and bioinformatics tools, 10KP will catalogue the genome content of plant and protist diversity and make these data freely available as an enduring foundation for future scientific discoveries and applications. 10KP is structured as an international consortium, open to the global community, including botanical gardens, plant research institutes, universities, and private industry. Our immediate goal is to establish a policy framework for this endeavor, the principles of which are outlined here.
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