Isolation of enteric pathogens from asymptomatic students from the United States and Latin America.
Isolation of enteric pathogens from asymptomatic students from the United States and Latin America.
复制标题
从来自美国和拉丁美洲的无症状学生中分离肠道病原体。
DOI：
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发表时间：
1977
影响因子：
6.4
通讯作者：
J. Olarte
中科院分区：
文献类型：
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作者：
L. Pickering;H. Dupont;D. Evans;D. Evans;J. Olarte
在一项正在进行的评估腹泻发病率和病因学的研究中，每三天对来自墨西哥一所大学的223名学生的粪便标本进行一次为期60天的肠道细菌和原虫病原体的评估。从223名无症状学生中的83名（37%）粪便中分离出一种或多种肠道病原体。与其他学生群体相比，从美国新来的暑期学生中分离出的病原体数量显著（P < 0.005），包括在墨西哥呆了一年以上的美国学生。志贺菌菌株分离自27（12%）的223名学生入学，并有关于志贺菌分离各学生群体之间没有显着差异。产毒素大肠杆菌和沙门氏菌从美国的暑期学生中分离出的数量显著高于其他学生群体（P < 0.005）。在大量无症状学生粪便中发现肠道病原体表明肠道病原体的存在不一定与疾病有关。健康的短暂携带者可能是细菌的重要储存库和传播方式，这些细菌与旅行者腹泻的原因有关。从美国新来的旅行者似乎比拉丁美洲人更容易受到E。产生不耐热肠毒素的大肠杆菌。
Specimens of stools from 223 students attending a Mexican university were evaluated every three days for 60 days for the presence of enteric bacterial and protozoal pathogens during an ongoing study evaluating the incidence and etiology of diarrhea. One or more enteric pathogens were isolated from stools of 83 (37%) of 223 asymptomatic students. A pathogen was isolated from a significantly (P < 0.005) greater number of newly arrived summer students from the United States compared with that in other student groups, including students from the United States who had been in Mexico for more than one year. A shigella strain was isolated from 27 (12%) of 223 students enrolled, and there was no significant difference with regard to isolation of Shigella among various student groups. Toxigenic Escherichia coli and Salmonella were isolated from a significantly (P < 0.005) greater number of summer students from the United States compared with that in other student groups. The finding of enteric pathogens in stools of a large number of asymptomatic students indicates that the presence of enteric pathogens need not be associated with disease. Healthy transient carriers may be an important reservoir for and mode of spread of bacteria implicated as the cause of travelers' diarrhea. The newly arrived traveler from the United States appears to be more susceptible than Latin Americans to colonization by E. coli that produce heat-labile enterotoxin.