Sleep problems and psychological distress in family members of patients with hematological malignancies in the Japanese population.
Sleep problems and psychological distress in family members of patients with hematological malignancies in the Japanese population.
复制标题
日本血液系统恶性肿瘤患者家属的睡眠问题和心理困扰。
DOI：
10.1007/s00277-014-2139-4
复制
发表时间：
2014
期刊：
影响因子：
3.5
通讯作者：
Kishi A.
中科院分区：
文献类型：
--
作者：
Tanimukai H;Hirai K;Adachi H;Kishi A.
癌症患者经常患有失眠症状，此外，他们的家人也经常经历这些症状。摘要本研究旨在探讨血液系统恶性肿瘤患者家属及患者失眠症状的发生率。我们进行了一项观察性横断面研究，使用临床自我报告问卷调查睡眠状况，抑郁症状（两个问题的方法）和担忧（来自简明癌症担忧清单的五个项目）。调查了112名家庭成员和153名患者。采用Attest和卡方检验比较家属与患者失眠和抑郁症状的患病率。Logistic回归分析用于确定失眠症状或与患者疾病相关的担忧是否对抑郁症状有影响。家属失眠症状的出现率（87%）明显高于患者（60%，p<0. 001）。家庭成员中抑郁情绪和快感缺乏的患病率分别为55%和34%，这些值高于患者（分别为43%和28%）。失眠症状和对当前/未来疾病状况的担忧与抑郁情绪显著相关（失眠症状，优势比（OR）4.3，可信区间（CI）1.2- 15.2，p = 0.025;担忧，OR 4.4，CI 1.0- 19.3，p = 0.048）。总之，我们的研究结果表明，失眠症状和抑郁症状是非常普遍的家庭成员以及血液恶性肿瘤患者。
Patients with cancer frequently suffer from insomnia symptoms, and additionally, their family members also often experience these symptoms. The aim of this study was to investigate the prevalence of insomnia symptoms in both family members and patients with hematological malignancies. We conducted an observational cross-sectional study using a clinical self-reported questionnaire for sleep conditions, depressive symptoms (two-question method), and worries (five items that originated from the Brief Cancer Worry Inventory). One hundred twelve family members and 153 patients were investigated. Attest and Chi-square test were used to compare the prevalence of insomnia and depressive symptoms between family members and patients. Logistic regression was used to determine whether insomnia symptoms or worries related to patients’ disease had an impact on depressive symptoms. The presence of insomnia symptoms in family members (87 %) was significantly higher than that in patients (60 %,p< 0.001). The prevalence of depressive mood and anhedonia in family members were 55 and 34 %, respectively, and these values were higher than those in patients (43 and 28 %, respectively). Insomnia symptoms and worries about present/prospective disease conditions were significantly associated with depressive mood (insomnia symptoms, odds ratios (OR) 4.3, confidence intervals (CI) 1.2–15.2,p= 0.025; worries, OR 4.4, CI 1.0–19.3,p= 0.048). Taken together, our results demonstrated that insomnia symptoms and depressive symptoms are highly prevalent in family members as well as in patients with hematological malignancies.