Diet and Diabetic Kidney Disease: Plant Versus Animal Protein.
Diet and Diabetic Kidney Disease: Plant Versus Animal Protein.
复制标题
饮食和糖尿病肾病：植物蛋白与动物蛋白。
DOI：
10.1007/s11892-017-0843-x
复制
发表时间：
2017
影响因子：
4.2
通讯作者：
HillGallant,KathleenM
中科院分区：
文献类型：
--
作者：
Moorthi,RanjaniN;Vorland,ColbyJ;HillGallant,KathleenM
本综述的目的是概述植物性饮食在延缓糖尿病肾病（DKD）进展方面有效性的证据。最近的发现膳食蛋白质的理想量一直是DKD患者的一个有争议的话题。较小的研究集中在蛋白质来源，植物和动物，以防止进展。有限的证据表明，注重植物性食物、低加工食品或低晚期糖基化终产物（AGE）的饮食模式可能有助于预防DKD进展。增加植物性食物，结合限制加工食品的饮食模式，或潜在地降低饮食中AGE的含量可能有利于DKD的饮食管理。然而，专门针对DKD治疗的饮食研究很少。此外，需要大型试验来评估包括肾功能变化、终末期肾病和死亡率在内的结果，以为这些饮食提供更实质性的证据。
Purpose of ReviewThe goal of this review is to present an overview of the evidence on the effectiveness of plant-based diets in delaying progression of diabetic kidney disease (DKD).Recent FindingsThe ideal quantity of dietary protein has been a controversial topic for patients with DKD. Smaller studies have focused on protein source, plant versus animal, for preventing progression. Limited evidence suggests that dietary patterns that focus on plant-based foods, those that are lower in processed foods, or those that are lower in advanced glycation end products (AGE) may be useful in prevention of DKD progression.SummaryIncreasing plant-based foods, incorporating diet patterns that limit processed foods, or potentially lowering AGE contents in diets may be beneficial for dietary management of DKD. However, dietary studies specifically targeted at DKD treatment are sparse. Further, large trials powered to assess outcomes including changes in kidney function, end-stage kidney disease, and mortality are needed to provide more substantial evidence for these diets.