How long do most seizures last? A systematic comparison of seizures recorded in the epilepsy monitoring unit
How long do most seizures last? A systematic comparison of seizures recorded in the epilepsy monitoring unit
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DOI：
10.1111/j.1528-1167.2006.00622.x
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发表时间：
2006-09-01
期刊：
影响因子：
5.6
通讯作者：
Sperling, Michael R.
中科院分区：
文献类型：
--
作者：
Jenssen, Sigmund;Gracely, Edward J.;Sperling, Michael R.
目的：需要更多关于癫痫发作通常持续多长时间的信息，因为这会影响治疗决策。癫痫发作类型及其他因素可影响癫痫发作持续时间。方法：随机抽取患者进行连续录像和头皮脑电图检查。癫痫发作持续时间定义为从癫痫发作早期体征（临床或EEG）至EEG显示癫痫发作结束的时间。癫痫发作分为简单部分性（SPS）、复杂部分性（CPS）、继发性全身强直-阵挛性（SGTCS）、原发性全身强直-阵挛性（PGTCS）和强直性（TS）。SGTCS分为复杂部分（SGTCS/CP）和强直阵挛部分（SGTCS/TC）。使用每种癫痫发作类型的中位持续时间和最长持续时间。结果：159例成人癫痫患者共发生癫痫发作579次，其中癫痫发作类型、首次发作和末次发作、发作部位、发作状态等进行了比较。部分发作蔓延到两个半球的癫痫发作持续时间最长。SGTCS不可能持续超过660 s，CPS不可能超过600 s，SPS不可能超过240 s。PGTCS和TS的持续时间较短，但这两种类型的受试者人数较少。CPS没有不同的持续时间根据睡眠状态在发病时，也没有一方origin.Conclusion：一个工作的定义癫痫持续状态的成人隐源性或症状性癫痫可以从这些数据中得出为未来的流行病学研究的目的。需要更多关于特发性癫痫和儿童的信息。
Purpose: More information is needed regarding how long seizures typically last, since this influences treatment decisions. Seizure type and other factors could influence seizure duration.Methods: Data were collected from a random sample of patients being evaluated with continuous video and scalp EEG. Seizure duration was defined as time from early sign of seizure (clinical or EEG) until the end of seizure on EEG. Seizures were categorized as simple partial (SPS), complex partial (CPS), secondarily generalized tonic-clonic (SGTCS), primary generalized tonic-clonic (PGTCS) and tonic (TS). SGTCS were divided into a complex partial part (SGTCS/CP) and a tonic-clonic part (SGTCS/TC). Median and longest duration of each seizure type in each individual were used. Comparisons of seizure types, first and last seizure, area of onset, and state of onset were performed.Results: Five hundred seventy-nine seizures were recorded in 159 adult patients. Seizures with partial onset spreading to both hemispheres had the longest duration. SGTCS were unlikely to last more than 660 s, CPS more than 600 s, and SPS more than 240 s. PGTCS and TS had shorter durations, but the number of subjects with those two types was small. CPS did not differ in duration according to sleep state at onset nor side of origin.Conclusion: A working definition of status epilepticus in adults with cryptogenic or symptomatic epilepsy can be drawn from these data for purposes of future epidemiologic research. More information is needed for the idiopathic epilepsies and in children.