Exercise Hemodynamics of Pulmonary Valvular Stenosis: Study of 64 Children
Exercise Hemodynamics of Pulmonary Valvular Stenosis: Study of 64 Children
复制标题
肺动脉瓣狭窄的运动血流动力学：64 名儿童的研究
作者：
J. Moller;Satyanarayana Rao;R. V. Lucas
本文对64例肺动脉瓣狭窄患儿进行了静息和运动时心导管检查。较轻的狭窄程度与右室功能正常有关，而较严重的狭窄与固定的卒中指数、RVEDP升高和心脏指数反应不佳有关。这些变化是由于右室顺应性改变所致。在一些患者中，顺应性异常与心肌肥大有关，而在4名患者中，顺应性异常最有可能是由心肌纤维化引起的。
Sixty-four children with pulmonary stenosis were studied by cardiac catheterization both at rest and on exercise. Whereas milder degrees of stenosis were associated with normal right ventricular function, more severe stenosis was associated with fixed stroke index and elevated RVEDP, and suboptimal response of cardiac index. These changes result from altered right ventricular compliance. In several the compliance abnormality was related to myocardial hypertrophy, whereas in four patients it was most likely caused by myocardial fibrosis.