Ciliary photoreceptors with a vertebrate-type opsin in an invertebrate brain
Ciliary photoreceptors with a vertebrate-type opsin in an invertebrate brain
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DOI：
10.1126/science.1099955
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发表时间：
2004-10-29
期刊：
影响因子：
56.9
通讯作者：
Wittbrodt, J
中科院分区：
文献类型：
--
作者：
Arendt, D;Tessmar-Raible, K;Wittbrodt, J
对于视觉，昆虫和脊椎动物的眼睛分别使用横纹和纤毛感光细胞。这些细胞显示出不同的结构，并通过不同的光转导级联来传递光信号。在海洋沙虫Platynereis中，我们发现了两种细胞类型：眼睛中的横纹感光细胞和大脑中的纤毛感光细胞。后者使用与脊椎动物视杆细胞和视锥细胞视蛋白密切相关的色素。比较分析表明，这两种类型的光感受器，不同的视蛋白，共存于Urbilateria，最后的共同祖先的昆虫和脊椎动物，并揭示了新的光脊椎动物眼睛的进化。
For vision, insect and vertebrate eyes use rhabdomeric and ciliary photoreceptor cells, respectively. These cells show distinct architecture and transduce the light signal by different phototransductory cascades. In the marine rag-worm Platynereis, we find both cell types: rhabdomeric photoreceptor cells in the eyes and ciliary photoreceptor cells in the brain. The latter use a photopigment closely related to vertebrate rod and cone opsins. Comparative analysis indicates that both types of photoreceptors, with distinct opsins, coexisted in Urbilateria, the last common ancestor of insects and vertebrates, and sheds new light on vertebrate eye evolution.