Non-coding RNAs in necroptosis, pyroptosis and ferroptosis in cancer metastasis.

Non-coding RNAs in necroptosis, pyroptosis and ferroptosis in cancer metastasis.
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DOI:
10.1038/s41420-021-00596-9
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发表时间:
2021-08-11
影响因子:
7
通讯作者:
Yang Z
Yang Z
中科院分区:
医学2区
文献类型:
--
作者:
Liu Y;Chen Q;Zhu Y;Wang T;Ye L;Han L;Yao Z;Yang Z

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远处转移是癌症患者死亡的主要原因。新近发现的程序性细胞死亡包括坏死性下垂、下垂和铁性下垂,在肿瘤转移过程中具有重要作用。同时,广泛报道非编码RNA精确调控程序性死亡和肿瘤转移。本文综述了肿瘤转移过程中坏死性下垂、热解性下垂和铁下垂的功能和作用,以及包括非编码RNA在内的坏死性下垂、下垂和铁下垂在肿瘤转移过程中的调控因素。
Distant metastasis is the main cause of death for cancer patients. Recently, the newly discovered programmed cell death includes necroptosis, pyroptosis, and ferroptosis, which possesses an important role in the process of tumor metastasis. At the same time, it is widely reported that non-coding RNA precisely regulates programmed death and tumor metastasis. In the present review, we summarize the function and role of necroptosis, pyrolysis, and ferroptosis involving in cancer metastasis, as well as the regulatory factors, including non-coding RNAs, of necroptosis, pyroptosis, and ferroptosis in the process of tumor metastasis.
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