Cancer of the pancreas. Diagnostic accuracy and survival statistics
Cancer of the pancreas. Diagnostic accuracy and survival statistics
复制标题
胰腺癌。
作者：
B. Gudjonsson;E. Livstone;H. Spiro
我们回顾了100例胰腺癌患者的自然病史、诊断的可靠性和生存率，并对胰腺癌治疗后生存率的文献进行了全面回顾。胰腺癌诊断的组织学确认有40 - 62.5%的错误。手术时仅凭检查和触诊的误差可能高达25%。根据代表约15，000例患者的61项临床研究计算的绝对5年生存率为0.4%。基于胰腺癌患者的总人群，当前文献中最好的系列的5年率仅为3%。世界文献中12.3%的5年生存者没有接受根治性手术。这项研究表明，报告方法必须标准化。同一患者和幸存者不应在不同报告中重复使用。一些作者声称胰腺切除术是最有效的姑息治疗，但死亡率最高。Cancer 42：2494-2506，1978.
We have reviewed the natural history, reliability of diagnosis, and survivorship of 100 patients with adenocarcinoma of the pancreas, in the context of a thorough review of the literature on survival after therapy for adenocarcinoma of the pancreas. There is 40‐62.5% error in the histologic confirmation of the diagnosis of pancreatic cancer. The error by inspection and palpation alone at the time of surgery may be as great as 25%. The absolute 5 year survival rate calculated from 61 clinical studies representing approximately 15,000 patients is 0.4%. The best series in the current literature has only 3% 5 year rate based upon the total population of pancreatic cancer patients. 12.3% of 5 year survivors from the world literature did not have curative surgery. This study shows the necessity for standardization of reporting methods. The same patients and survivors should not be used repeatedly in different reports. Some authors who claim the most effective palliation by pancreatic resection have the highest mortality rates. Cancer 42:2494–2506, 1978.