A novel multifunctional nano-platform with enhanced anti-cancer and photoacoustic imaging modalities using gold-nanorod-filled silica nanobeads

A novel multifunctional nano-platform with enhanced anti-cancer and photoacoustic imaging modalities using gold-nanorod-filled silica nanobeads
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DOI:
10.1039/c2cc37702k
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发表时间:
2013-01-01
影响因子:
4.9
通讯作者:
Liu, Dean-Mo
Liu, Dean-Mo
中科院分区:
化学2区
文献类型:
--
作者:
Chen, Po-Jung;Hu, Shang-Hsiu;Liu, Dean-Mo

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这种新颖的纳米海胆结构的特点是高密度和良好分散的金纳米棒在一个介孔二氧化硅纳米珠。这种纳米平台在体外和体内均提供了增加的光热稳定性、稳定的光声信号和高效的热疗效果,表明了强大的治疗诊断模式。
The novel nano-seaurchin structure is characteristic of high-density and well-dispersed gold nanorods in one mesoporous silica nanobead. This nanoplatform provided increased photothermal stability, stable photoacoustic signal and highly efficient hyperthermia effect both in vitro and in vivo, indicating a powerful theranostic modality.