Radial Shock Wave Devices Generate Cavitation.
Radial Shock Wave Devices Generate Cavitation.
复制标题
DOI：
10.1371/journal.pone.0140541
复制
发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Schmitz C
中科院分区：
文献类型：
--
作者：
Császár NB;Angstman NB;Milz S;Sprecher CM;Kobel P;Farhat M;Furia JP;Schmitz C
文献中的验证报告提出了一个问题，即径向体外冲击波治疗（rESWT）器械和振动按摩器械是否具有相似的能量特征，因此在治疗组织中引起相似的生物效应。我们使用激光光纤探头水听器（FOPH）测量、高速成像和X射线胶片分析来比较两种rESWT设备（瑞士DolorClast;瑞士尼翁的Electro Medical Systems; D-Actor 200;瑞士泰格维伦的Storz Medical）和振动按摩设备（Vibracare; G5/General Physiotherapy，Inc.，地球城，密苏里州，美国）。为了确认这些治疗方式的潜在生物效应，我们研究了rESWT和振动按摩装置对秀丽隐杆线虫（C. elegans）蠕虫。FOPH测量结果表明，两种rESWT器械产生的声波具有可比的压力和能量通量密度。此外，高速成像证明，两种rESWT装置都会产生气穴，并对X射线胶片表面造成机械损坏。振动按摩装置没有显示出任何这些特征。此外，C.在暴露于径向体外冲击波后，秀丽线虫在统计学上显著受损，但在蠕虫暴露于振动按摩装置后不受影响。本研究的结果表明，rESWT器械的能量特征和生物效应与振动按摩器械的能量特征和生物效应根本不同。先前的ESWT研究表明，用足够量的声学声波治疗的组织经历空化积聚、机械转导，并最终经历“启动”愈合反应的生物学改变。由于其不同的治疗适应症和禁忌症，rESWT器械不能等同于振动按摩器械，在临床实践中应谨慎使用。
Conflicting reports in the literature have raised the question whether radial extracorporeal shock wave therapy (rESWT) devices and vibrating massage devices have similar energy signatures and, hence, cause similar bioeffects in treated tissues. We used laser fiber optic probe hydrophone (FOPH) measurements, high-speed imaging and x-ray film analysis to compare fundamental elements of the energy signatures of two rESWT devices (Swiss DolorClast; Electro Medical Systems, Nyon, Switzerland; D-Actor 200; Storz Medical, Tägerwillen, Switzerland) and a vibrating massage device (Vibracare; G5/General Physiotherapy, Inc., Earth City, MO, USA). To assert potential bioeffects of these treatment modalities we investigated the influence of rESWT and vibrating massage devices on locomotion ability of Caenorhabditis elegans (C. elegans) worms. FOPH measurements demonstrated that both rESWT devices generated acoustic waves with comparable pressure and energy flux density. Furthermore, both rESWT devices generated cavitation as evidenced by high-speed imaging and caused mechanical damage on the surface of x-ray film. The vibrating massage device did not show any of these characteristics. Moreover, locomotion ability of C. elegans was statistically significantly impaired after exposure to radial extracorporeal shock waves but was unaffected after exposure of worms to the vibrating massage device. The results of the present study indicate that both energy signature and bioeffects of rESWT devices are fundamentally different from those of vibrating massage devices. Prior ESWT studies have shown that tissues treated with sufficient quantities of acoustic sound waves undergo cavitation build-up, mechanotransduction, and ultimately, a biological alteration that “kick-starts” the healing response. Due to their different treatment indications and contra-indications rESWT devices cannot be equated to vibrating massage devices and should be used with due caution in clinical practice.