The risk of measles, mumps, and varicella among young adults: a serosurvey of US Navy and Marine Corps recruits.
The risk of measles, mumps, and varicella among young adults: a serosurvey of US Navy and Marine Corps recruits.
复制标题
年轻人患麻疹、腮腺炎和水痘的风险：对美国海军和海军陆战队新兵的血清调查。
DOI：
10.2105/ajph.83.12.1717
复制
发表时间：
1993
影响因子：
12.7
通讯作者：
G. Gray
中科院分区：
文献类型：
--
作者：
J. Struewing;K. Hyams;J. Tueller;G. Gray
目标
为了评估疫情传播的风险并指导免疫政策，对一组年轻人进行了麻疹、腮腺炎和水痘抗体的血清阳性检测。
方法
1989年6月，对1533名美国海军和海军陆战队新兵进行了一项横断面研究。抗体状态用商业上可用的酶联免疫吸附试验确定。
结果
对15至29岁的美国人群进行直接的性别和种族调整后，麻疹的血清阴性率为17.8%，腮腺炎为12.3%，水痘为6.7%。白人中麻疹和腮腺炎的血清阴性率较高，而非白人中水痘的血清阴性率较高。来自美国50个州以外的新兵，特别是来自岛屿地区的新兵，更有可能缺乏水痘抗体。在所有疾病中，疫苗接种或疾病阳性史预测抗体状态的敏感度均低于90%。
结论
这些结果表明，仍有可能发生流行病，特别是麻疹，因此有必要制定强制性免疫政策。移民到美国，特别是来自岛屿地区的移民，可能是一个高危群体，可以从水痘疫苗接种中受益。
OBJECTIVES
To assess the risk of epidemic transmission and to guide immunization policy, the seroprevalence of antibody to measles, mumps, and varicella was determined in a group of young adults.
METHODS
A cross-sectional study of 1533 US Navy and Marine Corps recruits was conducted in June 1989. Antibody status was determined with commercially available enzyme-linked immunosorbent assays.
RESULTS
Direct sex and race adjustment to the 15- to 29-year-old US population resulted in seronegativity rates of 17.8% for measles, 12.3% for mumps, and 6.7% for varicella. Measles and mumps seronegativity rates were higher among Whites whereas varicella seronegativity was higher among non-Whites. Recruits enlisting from outside the 50 US states, especially those from island territories, were more likely to lack varicella antibody. The sensitivity of a positive history of vaccination or disease in predicting antibody status was less than 90% for all diseases.
CONCLUSIONS
These results suggest a continued potential for epidemics, especially of measles, and the need for mandatory immunization policies. Immigrants to the United States, especially those from island territories, may be a high-risk group that could benefit from varicella vaccination.
基于人群的水痘并发症研究。
影响因子：
8
作者：
Guess,HA;Broughton,DD;Melton3rd,LJ;Kurland,LT
通讯作者：
Kurland,LT