Copper-catalyzed enantioselective substitution of allylic carbonates with diboron:: An efficient route to optically active α-chiral allylboronates
Copper-catalyzed enantioselective substitution of allylic carbonates with diboron:: An efficient route to optically active α-chiral allylboronates
复制标题
DOI：
10.1021/ja076634o
复制
发表时间：
2007-12-05
影响因子：
15
通讯作者：
Sawamura, Masaya
中科院分区：
文献类型：
--
作者：
Ito, Hajime;Ito, Shinichiro;Sawamura, Masaya
描述了一种用于合成α-手性烯丙基硼酸酯的方法，其特征在于用二硼对容易获得的烯丙基碳酸酯进行Cu（I）催化的对映选择性取代。利用该方法，成功地合成了多种α-手性烯丙基硼酸酯，包括功能化烯丙基硼酸酯，具有高的对映体纯度。
A method for the synthesis of alpha-chiral allylboronates featuring the Cu(I)-catalyzed enantioselective substitution of readily available allylic carbonates with a diboron is described. Using this method, various alpha-chiral allylboronates, including functionalized allylboronates, were successfully synthesized, with high enantiomeric purity.