Recent Advances in Stereocontrolled Mannosylation: Focus on Glycans Comprising Acidic and/or Amino Sugars
Recent Advances in Stereocontrolled Mannosylation: Focus on Glycans Comprising Acidic and/or Amino Sugars
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DOI：
10.1002/tcr.202100201
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发表时间：
2021-10
期刊：
影响因子：
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通讯作者：
Catherine Alex;A. Demchenko
中科院分区：
文献类型：
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作者：
Catherine Alex;A. Demchenko
本文综述了近年来在β-连接甘露糖苷的立体选择性合成方面所取得的成就。由于合成挑战和治疗潜力，在许多糖缀合物、细菌多糖和藻酸盐中发现的这些ManNAc、ManA和ManNAcA残基一直引起糖科学界的兴趣。
The main focus of this review is to describe accomplishments made in the stereoselective synthesis of β‐linked mannosides functionalized with carboxyls or amines/amides. These ManNAc, ManA and ManNAcA residues found in many glycoconjugates, bacterial polysaccharides, and alginates have consistently captured interest of the glycoscience community both due to synthetic challenge and therapeutic potential.