COMPARISON OF THE LAMINA CRIBROSA IN MAMMALIAN SPECIES WITH GOOD AND WITH INDIFFERENT VISION*

COMPARISON OF THE LAMINA CRIBROSA IN MAMMALIAN SPECIES WITH GOOD AND WITH INDIFFERENT VISION*
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具有良好视力和较差视力的哺乳动物物种中筛板的比较*

DOI:
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发表时间:
1956
影响因子:
4.1
通讯作者:
K. Tansley
K. Tansley
中科院分区:
医学2区
文献类型:
--
作者:
K. Tansley

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在研究小鼠视神经鞘缺损的遗传过程中,我注意到即使在正常的小鼠中,筛板也发育不良。众所周知,筛板是胶原纤维、弹性纤维和神经胶质纤维的网络,部分地与巩膜连续,视神经纤维在穿过眼球后部的途中穿过巩膜(Salzmann,1912)。这个网络加强了眼球在什么否则将是一个非常薄弱的点。在小鼠中,有时存在网络的建议(图1),但纤维非常细,通常很难在切片中看到;它们不吸收胶原蛋白染色。人们试图通过使用特定的组织染色剂来发现这些纤维的性质。用azan和周期性Schiff法染色,在其他动物中得到了很好的结果,但在任何~ 44 μ m小鼠神经中,除了最基本的胶原形成外,没有显示任何胶原形成;通常结果是完全阴性。用于上皮组织染色的各种方法(Verhoeff苏木精,
IN the course of an investigation into the inheritance of coloboma of the optic nerve sheath in mice, I noticed that the lamina cribrosa is very poorly developed even in normal animals of this species. The lamina cribrosa, as is well known, is a net-work of collagen, elastic, and neuroglial fibres, partly continuous with the sclera through which the optic nerve fibres run on their way through the back of the eyeball (Salzmann, 1912). This network strengthens the eyeball at what would otherwise be a very weak spot. In the mouse a suggestion of a network is sometimes present (Fig. 1), but the fibres are extremely fine and often hard to see in sections; they do not take up collagen stains. An attempt was made to discover the nature of these fibres by the use of specific tissue stains. Staining with the azan and periodic Schiff aimethods, which give excellent reSUl s in other animals, failed to show any but the most rudimen7 ~~~~tary collagen development in any ~~ 44~ ji ~ ' mouse nerve; usutally the result /)~~ , was entirely negative. Various methods of staining for e laktic tissue (Verhoeff's haematoxylin,