Patterns of fMRI activity dissociate overlapping functional brain areas that respond to biological motion
Patterns of fMRI activity dissociate overlapping functional brain areas that respond to biological motion
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DOI：
10.1016/j.neuron.2006.02.004
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发表时间：
2006-03-16
期刊：
影响因子：
16.2
通讯作者：
Downing, PE
中科院分区：
文献类型：
--
作者：
Peelen, MV;Wiggett, AJ;Downing, PE
对他人行为和意图的准确感知对于在社交环境中成功互动至关重要。在功能磁共振成像中，支持这一过程的几个皮层区域选择性地对人体和面部的静态和动态显示做出反应。在这里，我们应用模式分析技术来达到对生物运动的神经反应的新理解。功能定义的身体、面部和运动选择视觉区域都对“点光”人体运动有显著反应。然而，引人注目的是，在逐体素的基础上，只有身体选择性与生物运动选择性相关。我们得出结论：(1)生物运动，通过从运动到结构的过程，涉及到静态人体形态分析的领域；(2)梭状回后区和颞下后沟的身体选择区与面部和运动选择区重叠，但又不同；(3)考虑多种选择性模式时，对利益区域发现的解释可能会发生实质性改变。
Accurate perception of the actions and intentions of other people is essential for successful interactions in asocial environment. Several cortical areas that support this process respond selectively in fMRI to static and dynamic displays of human bodies and faces. Here we apply pattern-analysis techniques to arrive at a new understanding of the neural response to biological motion. Functionally defined body-, face-, and motion-selective visual areas all responded significantly to "point-light" human motion. Strikingly, however, only body selectivity was correlated, on a voxel-by-voxel basis, with biological motion selectivity. We conclude that (1) biological motion, through the process of structure-from-motion, engages areas involved in the analysis of the static human form; (2) body-selective regions in posterior fusiform gyrus and posterior inferior temporal sulcus overlap with, but are distinct from, face- and motion-selective regions; (3) the interpretation of region-of-interest findings may be substantially altered when multiple patterns of selectivity are considered.