Abacavir/Dolutegravir/Lamivudine (Triumeq)-Induced Liver Toxicity in a Human Immunodeficiency Virus-Infected Patient.

Abacavir/Dolutegravir/Lamivudine (Triumeq)-Induced Liver Toxicity in a Human Immunodeficiency Virus-Infected Patient.
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DOI:
10.1093/ofid/ofx122
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发表时间:
2017
影响因子:
4.2
通讯作者:
Roxby AC
Roxby AC
中科院分区:
医学3区
文献类型:
--
作者:
Christensen ES;Jain R;Roxby AC

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在临床试验中尚未报告与Triumeq(阿巴卡韦/拉米夫定/度鲁特韦)相关的药物性肝损伤。我们报告一例人类免疫缺陷病毒感染患者与Triumeq暴露相关的肝毒性。临床医生应注意这些药物对急性和迟发性肝炎的风险。建议密切监测。
Drug-induced liver injury related to Triumeq (abacavir/lamivudine/dolutegravir) has not been reported in clinical trials. We report a case of hepatotoxicity related to Triumeq exposure in a human immunodeficiency virus–infected patient. Clinicians should remain aware of the risk for acute and late-onset hepatitis with these agents. Close monitoring is recommended.
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