Risk of psychological distress in parents of preterm children in the first year: evidence from the UK Millennium Cohort Study.
Risk of psychological distress in parents of preterm children in the first year: evidence from the UK Millennium Cohort Study.
复制标题
DOI：
10.1136/bmjopen-2015-007942
复制
发表时间：
2015-12-18
期刊：
影响因子：
2.9
通讯作者：
Quigley MA
中科院分区：
文献类型：
--
作者：
Carson C;Redshaw M;Gray R;Quigley MA
评估早产儿（PT；<37 孕周）的父母在产后9个月时是否面临心理困扰（PD）的过高风险，并探讨早产程度的影响。数据取自英国千禧队列研究，这是一个具有全国代表性的前瞻性队列，涵盖 2000 年至 2002 年出生的婴儿。包括 12 100 个家庭，其父母双方在招募时（产后 9 个月）都有完整的数据。母亲报告的出生时胎龄（以周为单位）分为：严重 PT（<32 周）、中度 PT（32-33 周）、晚期 PT（34-36 周）、早产（37-38 周）、足月（39-41 周）、过期（42 周）。 PD 使用改良的 Rutter Malaise Inventory 进行评估，这是一种经过验证的工具，已用于男性和女性评估焦虑和痛苦的程度。总体而言，7% 的家庭报告采用 PT 分娩； 12.1% 的母亲和 8.9% 的父亲在产后 9 个月时出现 PD 迹象。与足月婴儿的母亲相比，严重 PT 婴儿的母亲患 PD 的风险较高（未调整 OR 2.10（1.30 至 3.39；调整 OR 1.66（1.02 至 2.69））。中度或晚期 PT 婴儿的母亲患 PD 的风险没有明显增加。然而，早产儿的母亲也表现出轻微的 PD 风险超额（调整 OR 1.16（0.99 至 2.69））。未经调整的分析表明，与足月婴儿的父亲相比，严重和中度 PT 婴儿的父亲患 PD 的风险加倍，在中度 PT 组中调整后仍具有统计学意义（调整后的 OR1.98（1.20 至 3.29））。严重 PT 儿童的父母在产后 9 个月时患 PD 的风险也增加，早产儿的母亲也出现较高的风险。与足月婴儿的母亲相比的风险。
To assess whether the parents of babies born preterm (PT; <37 weeks completed gestation) are at excess risk of psychological distress (PD) at 9 months postpartum, and to explore the influence of the degree of prematurity. Data were drawn from the UK Millennium Cohort Study, a nationally representative prospective cohort of babies born in 2000–2002. 12 100 families with complete data available for both parents at recruitment (9 months postpartum) are included. Mothers report of gestational age at birth (in weeks) was grouped into: very PT (<32 weeks), moderately PT (32–33 weeks), late PT (34–36 weeks), early term (37–38 weeks), full-term (39–41 weeks), post-term (42 weeks). PD was assessed using a modified Rutter Malaise Inventory, a validated instrument that has been used in both men and women to assess levels of anxiety and distress. Overall, 7% of families reported a PT birth; 12.1% of mothers and 8.9% of fathers showed signs of PD at 9 months postpartum. The mothers of very PT infants had an increased risk of PD, compared with the mothers of full-term babies (unadjusted OR 2.10 (1.30 to 3.39; adjusted OR 1.66 (1.02 to 2.69)). Mothers of moderate or late PT babies had no apparent increased risk of PD. However, mothers of early term babies also showed a small excess risk of PD (adjusted OR 1.16 (0.99 to 1.36)). Unadjusted analysis suggested a doubling in the risk of PD in fathers of very and moderately PT babies, compared with fathers of full-term babies, which remains statistically significant after adjustment in the moderately PT group (adjusted OR1.98 (1.20 to 3.29)). The parents of very PT children are at an increased risk of PD at 9 months postpartum, and mothers of children born at early term also see an elevated risk compared with mothers of full-term babies.