Hyperthyroidism: a secondary cause of isolated systolic hypertension.
Hyperthyroidism: a secondary cause of isolated systolic hypertension.
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DOI：
10.1111/j.1524-6175.2006.05180.x
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发表时间：
2006-08-01
期刊：
影响因子：
--
通讯作者：
Mulloy, Anthony L
中科院分区：
文献类型：
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作者：
Prisant, L Michael;Gujral, Jaspal S;Mulloy, Anthony L
单纯收缩期高血压是最常见的高血压形式，尤其是在50岁或以上的患者中。但不清楚的是，单纯收缩期高血压还有继发性原因。甲状腺功能亢进症通过降低全身血管阻力、增加心率和增加心输出量来增加收缩压。甲状腺功能亢进症的潜在心血管后果包括房性心律失常（特别是房颤）、肺动脉高压、左心室肥大和心力衰竭。甲状腺功能亢进患者的高血压患病率高于甲状腺功能正常患者。甲亢患者夜间动态血压是否有钝性下降存在较大争议。治疗与收缩压、心率和心输出量的降低有关。
Isolated systolic hypertension is the most common form of hypertension, especially among patients 50 years or older. What is not appreciated is that there are secondary causes of isolated systolic hypertension. Hyperthyroidism increases systolic blood pressure by decreasing systemic vascular resistance, increasing heart rate, and raising cardiac output. Potential cardiovascular consequences of hyperthyroidism include atrial arrhythmias (especially atrial fibrillation), pulmonary hypertension, left ventricular hypertrophy, and heart failure. The prevalence of hypertension is greater among hyperthyroid patients than euthyroid patients. Whether there is a blunted nocturnal decline in ambulatory blood pressure among hyperthyroid patients is more controversial. Treatment is associated with a reduction in systolic blood pressure, heart rate, and cardiac output.