Evaluation of acquired color vision deficiency in retinal vein occlusion using the Rabin cone contrast test.
Evaluation of acquired color vision deficiency in retinal vein occlusion using the Rabin cone contrast test.
复制标题
使用拉宾锥对比测试评估视网膜静脉阻塞中获得性色觉缺陷。
DOI：
10.1007/s00417-021-05171-7
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发表时间：
2021
期刊：
影响因子：
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通讯作者：
Ohji M
中科院分区：
文献类型：
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作者：
Matsumoto R;Saishin Y;Ohji M
目的应用拉宾锥对比试验（RCCT）探讨视网膜静脉闭塞（RVO）患者获得性色觉缺陷（CVD）的情况。方法回顾性分析39例RVO所致黄斑水肿患者，经玻璃体内注射抗vegf药物治疗后，最佳矫正视力改善至20/20 Snellen VA或更高。通过RCCT和标准伪等色板-2 （SPP-2）评估获得的CVD。结果RVO眼的平均L、M、S颜色对比测试（CCT）得分显著低于正常眼（L CCTs分别为70.0±13.3比90.0±8.0，P< 0.01； M CCTs分别为85.0±16.6比95.0±5.7，P< 0.01； S CCTs分别为80.0±21.5比95.0±7.1，P< 0.01）。39例患者中25眼通过RCCT诊断为获得性CVD， 39例患者中15眼通过SPP-2诊断为获得性CVD。21例患者分别在两天内进行RCCT。第一天发现17只眼睛获得CVD，第二天发现10只眼睛获得CVD。获得性CVD改善9眼，无变化8眼，恶化2眼。结论RCCT显示RVO为CVD。在某些情况下，即使视力恢复到20/20，由RVO引起的获得性CVD也可以进一步改善。RCCT可能能够定量诊断获得性心血管疾病状态。
PurposeTo investigate acquired color vision deficiency (CVD) using the Rabin cone contrast test (RCCT) in patients with retinal vein occlusion (RVO).MethodsWe retrospectively evaluated 39 patients with macular edema due to RVO who were treated with intravitreal injections of anti-VEGF agents and demonstrated improvement of best-corrected visual acuity to 20/20 Snellen VA or better. The acquired CVD was evaluated by the RCCT and standard pseudo-isochromatic plates-part 2 (SPP-2).ResultsMean L, M, and S color contrast test (CCT) scores were significantly lower in RVO eyes than in the fellow eyes (L CCTs, 70.0 ± 13.3 vs. 90.0 ± 8.0, respectively,P< 0.01; M CCTs, 85.0 ± 16.6 vs. 95.0 ± 5.7, respectively,P< 0.01; S CCTs, 80.0 ± 21.5 vs. 95.0 ± 7.1, respectively,P< 0.01). Acquired CVD was diagnosed in 25 eyes of 39 patients by the RCCT and in 15 eyes of 39 patients by SPP-2. The RCCT was performed on two different days in 21 patients. It revealed acquired CVD in 17 eyes on the first day and in 10 eyes on the second day. Acquired CVD was improved in 9 eyes, unchanged in 8 eyes, and worsened in 2 eyes.ConclusionsThe RCCT revealed eyes with RVO had acquired CVD. Acquired CVD caused by RVO can be improved further in some cases even after recovery of vision to 20/20. The RCCT may be able to quantitatively diagnose acquired CVD status.