Cardiovascular Precision Medicine in the Genomics Era.
Cardiovascular Precision Medicine in the Genomics Era.
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DOI：
10.1016/j.jacbts.2018.01.003
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发表时间：
2018-04
期刊：
影响因子：
--
通讯作者：
Ashley EA
中科院分区：
文献类型：
--
作者：
Dainis AM;Ashley EA
Precision medicine strives to delineate disease using multiple data sources—from genomics to digital health metrics—in order to be more precise and accurate in our diagnoses, definitions, and treatments of disease subtypes. By defining disease at a deeper level, we can treat patients based on an understanding of the molecular underpinnings of their presentations, rather than grouping patients into broad categories with one-size-fits-all treatments. In this review, the authors examine how precision medicine, specifically that surrounding genetic testing and genetic therapeutics, has begun to make strides in both common and rare cardiovascular diseases in the clinic and the laboratory, and how these advances are beginning to enable us to more effectively define risk, diagnose disease, and deliver therapeutics for each individual patient.
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