MOTUPORIN, A POTENT PROTEIN PHOSPHATASE INHIBITOR ISOLATED FROM THE PAPUA-NEW-GUINEA SPONGE THEONELLA-SWINHOEI GRAY
MOTUPORIN, A POTENT PROTEIN PHOSPHATASE INHIBITOR ISOLATED FROM THE PAPUA-NEW-GUINEA SPONGE THEONELLA-SWINHOEI GRAY
复制标题
DOI：
10.1016/s0040-4039(00)91674-5
复制
发表时间：
1992-03-17
影响因子：
1.8
通讯作者：
ALLEN, TM
中科院分区：
文献类型：
--
作者：
DESILVA, ED;WILLIAMS, DE;ALLEN, TM
Motuporin（1）是一种环状五肽，是一种有效的蛋白磷酸酶-1抑制剂和细胞毒素，已从采集于巴布亚新几内亚的海绵Theonella swinhoei中分离得到。 通过光谱分析和化学降解鉴定了motuporin的结构。
Motuporin (1), a cyclic pentapeptide that is a potent protein phosphatase-1 inhibitor and cytotoxin, has been isolated from the marine sponge Theonella swinhoei collected in Papua New Guinea. The structure of motuporin was elucidated by spectroscopic analysis and chemical degradation.