Platelet transfusions in adult patients with particular reference to patients undergoing surgery

Platelet transfusions in adult patients with particular reference to patients undergoing surgery
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成人患者的血小板输注,特别是接受手术的患者

DOI:
10.1111/j.1365-3148.2009.00970.x
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发表时间:
2010
影响因子:
1.5
通讯作者:
T. Mäki
T. Mäki
中科院分区:
医学4区
文献类型:
--
作者:
R. Palo;L. Capraro;R. Hanhela;M. Koivuranta;L. Nikkinen;M. Salmenperä;I. Salonen;S. Sjövall;A. Tienhaara;M. Vähämurto;T. Mäki

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总结。关于血小板(PLT)接受者的描述性信息,特别是在手术期间,是有限的。需要对当前PLT输注患者的流行病学进行描述,以优化血小板输注护理并跟踪PLT使用的趋势。在2004年和2005年,来自几个计算机化医疗系统的信息被组合在一起。参与医院(21个9个医院区)处理了约占芬兰年度住院人数的%。共有6321名成人患者接受了37761个PLT产品的输注。血液病患者输注PLT产品最多(43.1%)。只有1.0%的外科患者接受了PLT(53.8%的PLT受体和35.8%的输血PLT)。输注PLT最常见的单次手术是冠状动脉搭桥术,而27·1%的手术相关PLT是给与消化系统或脾的手术。在所有接受PLT输注(手术和保守治疗)的患者中,只有36.4%的患者直接出院;住院死亡率为9.5%。2004年,每1000名需要手术的住院患者中,PLT获得了40种产品,2005年为38种产品。成人患者围手术期PLT使用量略有减少。作为一种单一的手术类型,冠状动脉搭桥术患者接受了大部分的PLT产品,多年来PLT的使用量没有下降。总体而言,接受PLT的患者住院死亡率较高。
summary. Descriptive information on platelet (PLT) recipients, particularly during surgery, is limited. A description of the current epidemiology of PLT‐transfused patients is required to optimize platelet transfusion care and to follow trends in PLT use. In 2004 and 2005, information was combined from several computerized medical systems. Participating hospitals (9 hospital districts of 21) handled approximately 64% of annual Finnish hospital admissions. A total of 6321 adult patients were transfused with 37 761 PLT products. Most PLT products (43·1%) were transfused to patients suffering from haematological malignancies. Only 1·0% of all surgical patients received PLTs (53·8% of PLT recipients and 35·8% of transfused PLTs). The most common single operation connected with PLT transfusion was coronary artery bypass while 27·1% of surgery‐related PLTs were given to patients having an operation involving the digestive system or spleen. Only 36·4% of all PLT‐transfused (operated and conservatively treated) patients were discharged directly home; in‐hospital mortality was 9·5%. PLTs were given 40 products per 1000 hospital admissions requiring an operation in 2004, and 38 products in 2005. Perioperative PLT use is slightly decreasing in adult patients. As a single‐operation type, coronary artery bypass patients receive most of the PLT products and have experienced no decline in PLT use over the years. Overall, PLT recipients have high in‐hospital mortality.