Axon diameter relates to synaptic bouton size: structural properties define computationally different types of cortical connections in primates

Axon diameter relates to synaptic bouton size: structural properties define computationally different types of cortical connections in primates
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DOI:
10.1007/s00429-016-1266-1
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发表时间:
2017-04-01
影响因子:
3.1
通讯作者:
Caminiti, Roberto
Caminiti, Roberto
中科院分区:
医学3区
文献类型:
--
作者:
Innocenti, Giorgio M.;Caminiti, Roberto

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神经连接是由不同直径的轴突实现的,其频谱随物种和区域的不同而增加。轴突直径决定传导速度,并与起始细胞体的大小成正比。我们描述了在运动中,猴的厚轴突的膝盖骨连接比细轴突分布的更大,这表明更快的轴突在它们的末端也释放更多的神经递质,可能更强大地激活它们的目标。
Neural connections are implemented by axons of different diameters, whose spectrum increases depending on species and areas. Axon diameter determines conduction velocity and is proportional to the size of the cell body of origin. We describe that in motor, callosal connections of the monkey thick axons distribute larger boutons than thin axons, suggesting that faster axons also release more neurotransmitter at their termination, probably activating more powerfully their targets.