Adult neurogenesis: VCAM stems the tide.

Adult neurogenesis: VCAM stems the tide.
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成人神经发生:VCAM 遏制潮流。

DOI:
10.1016/j.stem.2012.07.012
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发表时间:
2012
期刊:
影响因子:
23.9
通讯作者:
Lehtinen,MariaK
Lehtinen,MariaK
中科院分区:
医学1区
文献类型:
--
作者:
Lehtinen,MariaK

文献摘要

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In this issue ofCell Stem Cell, Kokovay et al. uncover that VCAM1 expression in neural stem cells regulates adult neurogenesis. Cerebrospinal fluid-borne IL-1β upregulates VCAM1 expression, which in turn regulates the architecture of the stem cell niche, redox homeostasis, and neurogenesis.