A historical perspective of template-based protein structure prediction.
A historical perspective of template-based protein structure prediction.
复制标题
基于模板的蛋白质结构预测的历史视角。
DOI：
10.1007/978-1-59745-574-9_1
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
Xu,Ying
中科院分区：
文献类型：
--
作者：
Guo,Jun-Tao;Ellrott,Kyle;Xu,Ying
This chapter presents a broad and a historical overview of the problem of protein structure prediction. Different structure prediction methods, including homology modeling, fold recognition (FR)/protein threading, ab initio/de novo approaches, and hybrid techniques involving multiple types of approaches, are introduced in a historical context. The progress of the field as a whole, especially in the threading/FR area, as reflected by the CASP/CAFASP contests, is reviewed. At the end of the chapter, we discuss the challenging issues ahead in the field of protein structure prediction.
