Noninvasive in vivo demonstration of the connections of the human parahippocampal gyrus
Noninvasive in vivo demonstration of the connections of the human parahippocampal gyrus
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DOI：
10.1016/j.neuroimage.2004.01.011
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发表时间：
2004-06-01
期刊：
影响因子：
5.7
通讯作者：
Duncan, JS
中科院分区：
文献类型：
--
作者：
Powell, HWR;Guye, M;Duncan, JS
磁共振纤维束成像技术提供了一种无创研究体内白色物质通路的方法。在这项研究中，我们已经使用扩散张量成像（DTI）和快速行进纤维束成像（FMT）算法绘制的结构连接的人类海马旁回（PHG）在10名健康受试者，使用种子点选择在前海马旁回。我们的研究结果表明，海马旁回和前颞叶，眶额区，后颞叶和纹外枕叶之间的连接通过舌和梭状回。我们还首次证明了海马旁回和海马本身之间的非侵入性直接连接。这些结果与以前的动物组织学追踪研究一致。新皮质区和海马之间通过海马旁回的联系可能为记忆和高级视觉加工的理论模型提供结构基础。(C)2004年爱思唯尔公司All rights reserved.
MR tractography techniques provide a method for noninvasively studying white matter pathways in vivo. In this study we have used diffusion tensor imaging (DTI) and the fast marching tractography (FMT) algorithm to plot the structural connectivity of the human parahippocampal gyros (PHG) in 10 healthy subjects, using seed points selected in the anterior parahippocampal gyrus. Our results demonstrate connectivity between the parahippocampal gyrus and the anterior temporal lobe, orbitofrontal areas, posterior temporal lobe and extrastriate occipital lobe via the lingual and fusiform gyri. We also demonstrate for the first time noninvasively direct connectivity between the parahippocampal gyrus and the hippocampus itself. These results agree with previous histological tract-tracing studies in animals. The connections demonstrated between neocortical areas and the hippocampus via the parahippocampal gyrus may provide the structural basis for theoretical models of memory and higher visual processing. (C) 2004 Elsevier Inc. All rights reserved.