Aerobic plus resistance training was more effective in improving the visceral adiposity, metabolic profile and inflammatory markers than aerobic training in obese adolescents
Aerobic plus resistance training was more effective in improving the visceral adiposity, metabolic profile and inflammatory markers than aerobic training in obese adolescents
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DOI：
10.1080/02640414.2014.900692
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发表时间：
2014-01-01
影响因子：
3.4
通讯作者：
de Mello, Marco Tulio
中科院分区：
文献类型：
--
作者：
Damaso, Ana Raimunda;da Silveira Campos, Raquel Munhoz;de Mello, Marco Tulio
本研究的目的是确定有氧+阻力训练(AT+RT)是否比有氧训练(AT)在降低肥胖青少年的炎症标志物和心血管风险方面更有效。研究对象为139名肥胖青少年，年龄15-19岁，体重指数(BMI)=95百分位数，接受为期1年的跨学科干预。随机分为两组：AT组(n=55)，AT+RT组(n=61)。采集血样分析血糖、胰岛素、血脂、瘦素和脂联素浓度。用稳态模型胰岛素抵抗指数(HOMA-IR)评估胰岛素抵抗。AT+RT组在降低体脂质量、低密度脂蛋白浓度(LDL-c)水平、皮下和内脏脂肪以及增加身体瘦肉量方面效果更好。事实上，观察到高瘦素血症的减少和脂联素浓度的增加，促进了瘦素/脂联素比率的改善。两种类型的运动都能改善重要的临床参数，但AT+RT在改善内脏肥胖度、代谢谱和炎症标志物方面比单独使用AT更有效，这表明AT+RT在控制儿科人群的腹内肥胖和心血管风险方面具有临床应用价值。
The purpose of this study was to determine whether aerobic plus resistance training (AT + RT) is more effective than aerobic training (AT) at reducing inflammatory markers and cardiovascular risk in obese adolescents. A total of 139 obese adolescents were enrolled, aged 15-19 years, body mass index (BMI) >= 95th percentile and participated in 1 year of interdisciplinary intervention. They were randomised into two groups: AT (n = 55), AT + RT (n = 61). Blood samples were collected to analyse glycaemia, insulin, the lipid profile, leptin and adiponectin concentrations. Insulin resistance was measured by homeostasis model assessment of insulin resistance index (HOMA-IR). The AT + RT group showed better results with regard to decreased body fat mass, low-density lipoprotein concentration (LDL-c) levels, subcutaneous and visceral fat and increased body lean mass. Indeed, a reduction of hyperleptinaemia and an increase in adiponectin concentrations, promoting an improvement in the leptin/adiponectin ratio, was observed. Important clinical parameters were improved in both types of exercise; however, AT + RT was more effective in improving the visceral adiposity, metabolic profile and inflammatory markers than AT alone, suggesting clinical applications for the control of intra-abdominal obesity and cardiovascular risk in the paediatric population.