Niobium pentachloride-silver perchlorate as an efficient catalyst in the Friedel-Crafts acylation and Sakurai-Hosomi reaction of acetals
Niobium pentachloride-silver perchlorate as an efficient catalyst in the Friedel-Crafts acylation and Sakurai-Hosomi reaction of acetals
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DOI：
10.1016/j.tet.2005.02.061
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发表时间：
2005-05-09
期刊：
影响因子：
2.1
通讯作者：
Nishida, A
中科院分区：
文献类型：
--
作者：
Arai, S;Sudo, Y;Nishida, A
描述了五氯化铌与银盐催化的傅克酰化反应。具有 Ac2O 或 Bz(2)O 的芳香族化合物可以顺利转化为相应的酮，产率良好至优异。该系统也适用于使用缩醛的樱井-细见反应。反应进行得相当快，以极好的收率得到所需的产物。 (c) 2005 Elsevier Ltd. 保留所有权利。
Friedel-Crafts acylation catalyzed by niobium pentachloride with silver salt is described. Aromatic compounds with Ac2O or Bz(2)O were smoothly converted into the corresponding ketones in good to excellent yields. This system was also applied to the Sakurai-Hosomi reaction using acetals. The reaction proceeded quite rapidly to give the desired products in excellent yields. (c) 2005 Elsevier Ltd. All rights reserved.