Experimental fascial autografting for the supraspinatus tendon defect: Remodeling process of the grafted fascia and the insertion into bone
Experimental fascial autografting for the supraspinatus tendon defect: Remodeling process of the grafted fascia and the insertion into bone
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DOI：
10.1067/mse.2002.120808
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发表时间：
2002-03-01
影响因子：
3
通讯作者：
Sawai, T
中科院分区：
文献类型：
--
作者：
Sano, H;Kumagai, J;Sawai, T
为了解自体筋膜瓣移植术后的组织学变化，在2 7只兔的棘上肌止止点附近形成1.5×1.5 cm的肌腱缺损区，并用自体筋膜瓣修复。分别于术后第1、2、3、4、6、8周取肩进行组织学和免疫组织化学检查。在筋膜-骨交界处，软骨细胞在术后2周开始出现，此后迅速增加。虽然没有发现潮汐标志，但直接植入纤维软骨的重建在8周时几乎完成。II型和III型胶原的分布与正常棘上肌腱止点相似。移植筋膜内细胞密度随时间延长明显增加(r(2)=0.7.4，P<0.0001)。我们的研究表明，肌腱组织及其附着点在该手术后都得到了改造。自体筋膜瓣移植修复冈上肌腱缺损可能是有用的。
To elucidate the postoperative histologic changes of fascial autografting, tendinous defects (1.5 X 1.5 cm) were created close to the suprospinatus insertion and were covered by fascial autografts in 2 7 rabbits. Shoulders harvested on the fourth cloy and 1, 2, 3, 4, 6, and 8 weeks after surgery were examined histologically and immunohistochemically. At the fascia-bone junction, chondrocytes started to appear at 2 weeks after surgery and increased rapidly thereafter. Although a tidemark was not seen, remodeling of direct insertion with fibrocartilage was almost complete by 8 weeks. The distribution of collagen types II and III represented a pattern similar to that of a normal suprospinatus tendon insertion. In the grafted fascia, the cellular density showed a marked increase over time (r(2) = 0.7.4, P < .0001). Our study revealed that both the tendinous tissue and its insertion were reformed after this procedure. Fascial autografting might be useful for repairing a supraspinatus tendon defect.