Successful replacement of a thrombosed mitral ball-valve prosthesis.
Successful replacement of a thrombosed mitral ball-valve prosthesis.
复制标题
成功更换血栓二尖瓣假体。
DOI：
10.1001/jama.1965.03090240083031
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发表时间：
1965
期刊：
影响因子：
--
通讯作者：
J. Reeves
中科院分区：
文献类型：
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作者：
F. Spencer;J. Trinkle;J. Reeves
自从1961年斯塔尔和爱德华兹发表了关于他们的球形人工瓣膜的初步临床经验的令人印象深刻的报告以来，它已经得到了广泛和成功的应用。2-5许多患者已经成功地从严重的充血性心力衰竭中康复。假体的主要局限性是在一些患者中由于假体上形成的凝块而形成外周栓塞。抗凝治疗明显降低了这种并发症的发生率，但确切的数据还没有。本报告描述了一个非常罕见的并发症，从一个球瓣假体：20个月后，一个增生的凝块产生急性阻塞二尖瓣。Garamella及其同事6在该患者就诊前几个月及时报告了一例具有致死性结局的类似病例，这使得有可能确立正确的诊断并成功置换血栓形成的假体。25岁白色女性1例
SINCE THE impressive report by Starr and Edwards 1 in 1961 of initial clinical experiences with their ball-valve prosthesis, it has been widely and successfully employed. 2-5 Many patients have been successfully rehabilitated from severe congestive heart failure. The main limitation of the prosthesis has been the development of peripheral emboli in some patients from clots forming on the prosthesis. Anticoagulant therapy has apparently decreased the frequency of this complication, though exact data are not yet available. This report describes a very rare complication from a ball-valve prosthesis: 20 months after operation a proliferating clot produced acute obstruction of the mitral valve. The timely report by Garamella and associates 6 of a similar case with a fatal outcome, which was published a few months before this patient was seen, made it possible to establish a correct diagnosis and successfully replace the thrombosed prosthesis. Report of a Case A 25-year-old white woman