HDlive imaging of the fetal face in fetuses with autosomal trisomics.
HDlive imaging of the fetal face in fetuses with autosomal trisomics.
复制标题
常染色体三体胎儿的胎儿面部 HDlive 成像。
DOI：
10.1007/s10396-014-0523-2
复制
发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Hata T
中科院分区：
文献类型：
--
作者：
Hanaoka U;Tanaka H;Koyano K;Uematsu R;Kanenishi K;Hata T
背景我们的目的是介绍我们的经验面部畸形重建采用传统的三维（3D）超声和HDlive胎儿常染色体三体。13三体1例，18三体3例，结果1例21-三体综合征患者孕29周5天出现上斜眼，使用HDlive观察到扁平的鼻子、低置的耳朵和向下的嘴角。在另外两例21三体综合征中，两种技术显示了相同的面部表现。在第27周和第6天的1例18三体病病例中，使用HDlive识别出了一个小脑袋，伴有头后部突出、耳朵位置低、下颌小、鼻子上翘、眼睑皱褶窄和眼睛间距宽。在另外两例18三体的病例中，与传统的3D超声相比，HDlive显示了胎儿面部更详细的特征。在31周和1天的13三体综合征的单一情况下，唇裂和近视眼都认识到与3D超声和HDlive.ConclusionHDlive可以提供更清晰的面部图像比传统的3D超声。特别是，由于其阴影效应，HDlive在描绘眼裂方面优于传统的3D超声，具有上级优势。HDlive可能是产前评估胎儿面部畸形的一种有用的诊断方式。
BackgroundOur objective is to present our experience of facial dysmorphism reconstructed employing conventional three-dimensional (3D) ultrasound and HDlive in fetuses with autosomal trisomies.MethodsSeven fetuses with autosomal trisomies (one case of trisomy 13, three of trisomy 18, and three of trisomy 21) at 16–38 weeks’ gestation were studied using 3D ultrasound and HDlive.ResultsIn one case of trisomy 21 at 29 weeks and 5 days, upward slanting eyes, a flattened nose, low-set ears, and the corners of the mouth turned down were noted employing HDlive. In the other two cases of trisomy 21, both techniques showed the same facial findings. In one case of trisomy 18 at 27 weeks and 6 days, a small head accompanied by a prominent back portion of the head, low-set ears, a small jaw, upturned nose, narrow eyelid folds, and widely spaced eyes were identified using HDlive. In the other two cases of trisomy 18, HDlive showed more detailed features of the fetal face compared to conventional 3D ultrasound. In the single case of trisomy 13 at 31 weeks and 1 day, cleft lip and close-set eyes were recognized with both 3D ultrasound and HDlive.ConclusionHDlive can provide clearer facial images than conventional 3D ultrasound. In particular, HDlive is superior to conventional 3D ultrasound for the depiction of eye fissures because of its shadowing effect. HDlive may be a useful diagnostic modality for the antenatal evaluation of subtle fetal facial dysmorphism.