Guidelines for the production, control and regulation of snake antivenom immunoglobulins

Guidelines for the production, control and regulation of snake antivenom immunoglobulins
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DOI:
10.1051/jbio/2009043
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发表时间:
2010-01-01
期刊:
Biologie Aujourd hui
影响因子:
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通讯作者:
Chippaux, Jean-Philippe
Chippaux, Jean-Philippe
中科院分区:
其他
文献类型:
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作者:
Chippaux, Jean-Philippe

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毒液蛰入虽然频繁和严重,但在大多数发展中国家是一个被忽视的公共卫生问题。抗蛇毒血清的供应情况很差,主要是在撒哈拉以南非洲,这仍然是世界卫生组织(世卫组织)的一个主要关切。自2007年以来,世卫组织委托国际专家提出准则,旨在改进抗蛇毒血清的生产、质量控制、登记和使用。这些准则不久将公布,应能促进抗蛇毒血清的获得和保健服务部门的使用,从而在短期内大幅度降低蛇咬伤的发病率和死亡率。
Although frequent and severe, envenomations represent a neglected public health problem in most of the developing countries. Access to antivenoms is poor, mainly in Sub-Saharan Africa, and remains a major concern to World Health Organization (WHO). Since 2007, WHO committed international experts to propose guidelines aiming to improve the manufacture, quality control, registration and use of antivenoms. These guidelines, which will published soon, should promote access to antivenoms, and their use by health services, leading in the short term to a significant decrease of snakebite morbidity and mortality.