Fixed eruptions: causative drugs and challenge tests
Fixed eruptions: causative drugs and challenge tests
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固定性喷发：致病药物和挑战测试
DOI：
10.1111/j.1365-2133.1985.tb15266.x
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发表时间：
1985
影响因子：
10.3
通讯作者：
S. Stubb
中科院分区：
文献类型：
--
作者：
K. Kauppinen;S. Stubb
已鉴定出导致 86 例固定性药疹病例的药物，除两例外，所有药物均通过挑战得到证实。该系列包括 16 例全身性大疱性固定性喷发病例，类似于莱尔综合征。在整个系列和最严重病例组中，主要致病药物是非那酮和巴比妥类药物。十年前芬兰的一份报告显示，同样的药物是最常见的致病因素。
The drugs responsible for eighty‐six cases of fixed drug eruption have been identified, and in all but two were confirmed by challenge. The series included sixteen cases of generalized bullous fixed eruption, which resembles Lyell's syndrome. The main causative drugs were phenazones and barbiturates, both in the series as a whole and in the group of the most severe cases. The same drugs were the most frequent causative agents in a report from Finland 10 years ago.