Four New Triterpenes from Fungus of Fomes officinalis
Four New Triterpenes from Fungus of Fomes officinalis
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药用真菌中的四种新三萜
DOI：
10.1248/cpb.57.195
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发表时间：
2009-02-01
影响因子：
1.7
通讯作者：
Yan, Ming
中科院分区：
文献类型：
--
作者：
Wu, Xia;Yang, Jun-Shan;Yan, Ming
在以前的工作中，我们报道了从药用木霉的CHCl3可溶部分中分离得到的五个羊毛烷型三萜。在对三氯甲烷可溶部位化学成分的进一步分离研究中，分离得到4个新的三萜类化合物：甲黄酮酸F(1)，6(2)和甲黄酮醇A(3)，B(4)，以及7个已知化合物：马钱子酸(5)，甲内酯A(6)，甲内酯B(7)，甲内酯C(8)，落叶松脂酸(9)，麦角甾醇(10)，麦角-7，22，二烯-3-β-醇(11)。通过波谱分析和包括核磁共振波谱技术(C-13，H-1，异核多量子相干(HMQC)，异核多键相关(HMBC)，相关光谱(COSY)和核Overhaser效应光谱(NOESY))等化学方法确定了新化合物的结构。
In the previous work we reported five lanostane-type triterpenes from the CHCl3 soluble fraction of Fomes officinalis. In further study on the isolation of constituents from the CHCl3 soluble fraction, four new triterpenes, fomefficinic acids F (1), 6 (2) and fomefficinols A (3), B (4), together with seven known compounds officinalic acid (5), fomlactone A (6), fomlactone B (7), fomlactone C (8), laricinolic acid (9), ergosterol (10), ergota-7,22,dien-3 beta-ol (11) were isolated. The structures of new compounds were determined by spectroscopic analyses and chemical methods including NMR spectroscopic techniques (C-13, H-1, heteronuclear multiple quantum coherence (HMQC), heteronuclear multiple bonding correlation (HMBC), correlation spectroscopy (COSY) and nuclear Overhauser effect spectroscopy (NOESY)).