Comorbidities in Psoriasis Patients
Comorbidities in Psoriasis Patients
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DOI：
10.1016/j.sder.2010.01.002
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发表时间：
2010-03-01
影响因子：
--
通讯作者：
Menter, Alan
中科院分区：
文献类型：
--
作者：
Kim, Noori;Thrash, Breck;Menter, Alan
银屑病是一种慢性炎症性疾病，影响约2%的一般人群。许多研究已经评估了银屑病患者中共病疾病和危险因素的患病率增加，包括肥胖、代谢综合征、心血管疾病、银屑病关节炎、自身免疫性疾病、精神疾病、肝病、吸烟、恶性肿瘤、慢性阻塞性肺病、睡眠呼吸暂停和酗酒。深入了解银屑病这些合并症的重叠发病机制，突出了免疫介导机制在这些疾病状态中的重要性。银屑病及其合并症，必须以多学科的方式进行处理，以有效和全面地了解，管理和治疗这种复杂疾病的患者。Semin Cutan Med Surg 29：10-15（C）2010 Elsevier Inc. All rights reserved.
Psoriasis is a chronic inflammatory disorder that affects approximately 2% of the general population. Numerous studies have evaluated the increased prevalence of comorbid diseases and risk factors in psoriatic patients, including obesity, metabolic syndrome, cardiovascular disease, psoriatic arthritis, autoimmune disease, psychiatric illness, liver disease, smoking, malignancy, chronic obstructive pulmonary disease, sleep apnea, and alcohol abuse. Insight into the overlapping pathogenesis of these comorbidities of psoriasis highlights the importance of immune-mediated mechanisms in these disease states. Psoriasis, with its comorbidities, must be approached in a multidisciplinary manner to effectively and comprehensively understand, manage, and treat those with this complex disorder. Semin Cutan Med Surg 29:10-15 (C) 2010 Elsevier Inc. All rights reserved.