Abnormalities of joint mobility and gait in children with autism spectrum disorders
Abnormalities of joint mobility and gait in children with autism spectrum disorders
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DOI：
10.1016/j.braindev.2012.02.005
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发表时间：
2014-02-01
影响因子：
1.7
通讯作者：
Rapin, Isabelle
中科院分区：
文献类型：
--
作者：
Shetreat-Klein, Maya;Shinnar, Shlomo;Rapin, Isabelle
目的：自闭症儿童的大运动功能异常是临床医生所熟知的，但没有得到太多的经验文献，除了刻板印象之外，也不是自闭症的诊断标准。我们记录了患有DSM IV自闭症谱系障碍（asd）的儿童以及年龄和性别匹配的典型发育同伴（平均年龄4岁6个月，范围22个月-10岁9个月）的步态特征、脚趾行走的流行程度、被动关节活动范围和行走年龄。方法：我们评估了肘关节、腕关节、掌骨、指关节和踝关节的最大活动范围，并拍摄了儿童走路和跑步的视频。两名神经学家盲诊断独立评分步态特征临床。结果：自闭症儿童的关节活动度显著提高（p < 0.002），步态异常较多（p < 0.0001），平均行走时间比非自闭症儿童晚1.6个月。解释：这项研究表明，应该将注意力集中在自闭症患者的运动异常、社交能力、沟通能力以及限制性和重复性行为上。运动缺陷增加了儿童的其他残疾。它们表明，自闭症谱系障碍影响中枢神经系统回路的范围比人们通常认为的要广。(C) 2012日本儿童神经病学学会。Elsevier B.V.版权所有。
Aims: Abnormalities of gross motor function in children with autism are well known to clinicians but have not received much empirical documentation and, with the exception of stereotypies, are not among its diagnostic criteria. We recorded the characteristics of gait and prevalence of toe walking, the range of passive joint mobility, and age at walking in children with DSM IV autism spectrum disorders (ASDs) and in age- and gender-matched typically developing peers (mean age 4 years 6 months, range 22 months-10 years 9 months). Methods: We evaluated maximum range of mobility at the elbow, wrist, metacarpo phalangeal, and ankle joints and videoed children walking and running. Two neurologists blind to diagnosis independently scored features of gait clinically. Results: Children with ASDs had significantly greater joint mobility (p < .002), more gait abnormalities (p < .0001), and on average walked 1.6 months later than their non-autistic peers. Interpretation: This study indicates that attention should be directed to motor abnormalities as well as sociability, communication, and restricted and repetitive behaviors in individuals with ASDs. Motor deficits add to children's other handicaps. They indicate that ASDs affect a broader range of central nervous system circuitry than often appreciated. (C) 2012 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.