Use and interpretation of somatic cell count data in dairy cows
Use and interpretation of somatic cell count data in dairy cows
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DOI：
10.1136/inpract.27.6.310
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发表时间：
2005-06-01
期刊：
影响因子：
0.3
通讯作者：
Green, M
中科院分区：
文献类型：
--
作者：
Bradley, A;Green, M
牛奶中存在的细胞，即所谓的“体细胞”，已经被认识和研究了很多年。超过95%的体细胞是白细胞，包括中性粒细胞、巨噬细胞和淋巴细胞。因此，体细胞计数（SCC）-即每毫升牛奶中体细胞的数量-是牛奶中白细胞浓度的有用代表。牛奶中的SCC被用作乳房健康的指标，因为它们反映了免疫反应，从而反映了感染的存在。SCC <100，000个细胞/ml通常被认为是“正常的”，反映了健康的乳腺，而SCC> 200，000个细胞/ml则提示细菌感染。尽管SCC升高是现有细菌感染的公认指标，但非常低的SCC与随后对临床乳腺炎的易感性增加相关。这表明体细胞可以提供保护免受细菌定植以及作为感染的标志物。本文重点介绍了如何将SCC用作衡量当前感染状态的管理工具-无论是在个体奶牛还是牛群水平。
THE presence of cells in bovine milk, so-called 'somatic cells', has been recognised and studied for many years. More than 95 per cent of somatic cells are leucocytes, including neutrophils, macrophages and lymphocytes. The somatic cell count (SCC) - that is, the number of somatic cells per millilitre of milk - is therefore a useful proxy for the concentration of leucocytes in milk. SCCs in milk are used as indicators of mammary health on the basis that they reflect an immune response and thus the presence of infection. An SCC of < 100,000 cells/ml is often considered to be 'normal', reflecting a healthy mammary gland, whereas an SCC of > 200,000 cells/ml is suggestive of bacterial infection. Although a raised SCC is an accepted indicator of an existing bacterial infection, a very low SCC has been associated with an increased subsequent susceptibility to clinical mastitis. This suggests that somatic cells may provide protection from bacterial colonisation as well as being a marker of infection. This article focuses on how SCCs may be used as a management tool for gauging current infection status - both at the individual cow and herd level.